药物自我处置能力训练对社区慢性精神分裂症患者的长期作用  

A long effects of self medication management skill training for chronic schizophrenic patients in community

作　　者：徐文炜[1] 查智群[1] 张紫娟[1] 吴世珍[1] 李达[1] 吴二南[1] 程明媚[1] 张凤娟[1] 张恒[1] 

机构地区：[1]南京医科大学附属无锡精神卫生中心精神科,江苏省无锡市214151

出　　处：《中国康复医学杂志》2007年第4期329-331,338,共4页Chinese Journal of Rehabilitation Medicine

基　　金：无锡市社会发展基金项目(CS050004)

摘　　要：目的:探讨药物自我处置能力训练对精神分裂症患者的长期影响。方法:病例取自4个街道中病程5年以上的精神分裂症患者113例。随机分配到药物处置能力训练组(以下简称“训练组”)50例和对照组63例。对训练组进行药物处置能力训练4周,随访1年。疗效评定包括服药依从性、住院次数、肇事次数、精神症状缓解程度和社会功能。评定量表采用阳性和阴性症状量表、日常生活能力量表、大体评定量表。结果:两组患者均完成研究进入结果分析。①训练组在经过药物处置能力训练后一年内的药物依从性是对照组的1.53倍(P=0.001),而对照组则有逐步下降的趋势。②训练组在训练后住院率、住院天数和肇事率都显著低于对照组。③训练组的精神症状改善以阴性症状更为明显(P=0.004)。④训练组大体评定量表得分明显高于对照组(P=0.033)。结论:药物处置能力训练能够提高慢性精神分裂症患者的药物依从性,改善患者的阴性症状、社会功能和社交技能。Objective： To explore the long effects of self medication management skill training on the treatment of chronic schizophrenic patients. Method： 113 chronic schizophrenic patients whose courses for 5 years in community were randomly assigned to two groups, 50 patients in medication management training group and 63 patients in control group. The training group patients took part in the training program for 4 weeks. All patients were followed-up for 1 year when the training program was fulfilled. Resnit：50 patients had fulfilled medication management training program and were involved in the analysis of results. （1）The medicine compliance in the training group were better than control group（P=0.001）.（2）The day and time of hospitalization in the training group were reduced significantly compared with that of control group. Meanwhile, the prevalence of create disturbances in the training group were reduced significantly compared with that of control group. （3）Negntive symptoms of the training group patients were improved significantly compared with that of control group （P=-0.004）. （4）Social function of the training group were increased significantly compared with that of control group （P=0.033）.Conclusion： Self medication management skill training had positive effects on the treatment and rehabilitation of chronic schizophrenic patients. The medicine compliance, negative symptoms of patients and social skills were also improved in these patients.

关 键 词：精神分裂症 药物处置能力训练 康复 

分 类 号：R749.3[医药卫生—神经病学与精神病学] R493[医药卫生—临床医学]