肝癌患者唾液中HCV抗体的检测  

The Test of HCV Antibody in Saliva of Primary Hepatocellular Carcinoma

作　　者：李忠培[1] 刘双斌 潘燕华[1] 

机构地区：[1]泰安市中心医院检验科,山东泰安271000 [2]泰安市第一人民医院妇产科,山东泰安271000

出　　处：《泰山医学院学报》2006年第5期455-456,共2页Journal of Taishan Medical College

摘　　要：目的探讨原发性肝癌(PHC)患者唾液中抗-HCV-IgG检测的可行性。方法采用酶联免疫吸附反应(ELISA)平行检测268例PHC患者唾液及血清中HCV抗体(抗-HCV)。结果PHC患者唾液及血清中抗-HCV-IgG检出率分别为14.55%(39/268)和15.29%(41/268)。两种标本阳性符合率为95.12%,阴性符合率100%。结论:检测唾液中抗-HCV-lgG简便易行,安全可靠。PHC患者唾液抗-HCV-lgG的检出,提示唾液可能成为丙肝感染途径之一,有助于PHC病因学、流行病学研究的深入开展。Objective ： To explore the possibility of the detection of anti - HCV - IgG in saliva of primary hepatocellular carcinoma. Methods： The method of ELISA is used to detect the antibody of HCV in saliva and serum of 268 cases of PHC. Result： The result shows that the anti - HCV - IgG was found through saliva test in 39 of 268 cases; accounting for 14. 55%, through serum test 41 of 268 cases, accounting for 15.29%. The positive agreement of anti -HCV -IgG in two samples occupies 95. 12%, with the negative agreement 100%. Detection of anti - HCV - IgG is easy,safe, and reliable. Conclusion： The determination of Anti - HCV - IgG in the saliva of PHC gives saliva the possibility of being a way of infection, which will contribute to the further research of etiology and epidemiology.

关 键 词：原发性肝癌 丙型肝炎病毒抗体 酶联免疫吸附反应 唾液 

分 类 号：R735.7[医药卫生—肿瘤]