DDLS视乳头损伤分期法与青光眼视野损害的相关性研究(英文)  

A study on correlation between the disc damage likelihood scale and visual field damage in glaucoma

作　　者：夏晓波[1] 周霞[1] 黄佩刚[1] 王平宝[1] 刘双珍[1] 

机构地区：[1]中南大学湘雅医院眼科,中国湖南省长沙市410008

出　　处：《国际眼科杂志》2007年第2期305-308,共4页International Eye Science

基　　金：中国湖南省卫生厅基金资助项目(No.C-2004-004)~~

摘　　要：目的:研究DDLS(disk damage like lihood scale)视乳头损伤分期法与开角型青光眼视野损害的相关性,探讨开角型青光眼的早期诊断方法。方法:利用Discam早期青光眼诊断仪彩色视乳头立体成像系统在Screen Vu立体观察镜下确定31例(58眼)开角型青光眼及29例(58眼)可疑青光眼患者视乳头的DDLS分期。所选患者均为中等大小视乳头(2.0～3.0mm)。利用Humphrey自动电脑视野分析仪30-2程序对上述患者进行视野检测,研究DDLS分期与视野指数平均缺损(MD,mean defect)、视野模式标准差(PSD,pattern standard deviation)及视野损害分期(HPASS,Hodapp-Parrish-Anderson staging system)的相关性。结果:对116眼中等大小视乳头(2.0～3.0mm)开角型青光眼及可疑青光眼患者研究发现,青光眼组DDLS分期与MD(Pearson,r=-0.664,P<0.000)、PSD(Pearson,r=0.554,P<0.000)及HPASS(Spearman,r=0.603,P<0.000)有相关性,相关系数具有统计学意义。可疑青光眼组DDLS分期与MD、PSD及HPASS分期无明显相关性。结论:DDLS视乳头损伤分期法与开角型青光眼视野损害的程度相关,DDLS视乳头损伤分期法有助于开角型青光眼的早期诊断。AIM： To determine the correlation between the disc damage likelihood scale and visual field damage in patients with open angle glaucoma（OAG）,and study the method of early diagnosis of OAG METHODS： Optic nerves of OAG （31 cases,58 eyes） and suspected glaucoma patients （29 cases,58 eyes） were photographed using a digital stereoscopic camera system （Discam, Marcher, Ltd, U.K.）. Disc damage likelihood scale （DDLS） stages in a screen Vu stereoscope .A system of the Humphrey Field Analyzer （program 30-2,USA） was used to obtain the mean deviation（MD） and pattern standard deviation（PSD） values. The correlations between DDLS and the visual field parameters was evaluated. Findings were assessed by the Pearson correlation coefficients. RESULTS： 116 eyes are with moderate optic nerves（2-3mm）. In 58 eyes with open angle glaucoma, the DDLS was significantly correlated with MD （Pearson,r=-0.664,P〈0.01） and PSD （Pearson, r=0.554, P〈0.01）. There was no significant correlation of these parameters in suspectious glaucoma patients. CONCLUSION： DDLS is significantly correlated with the degree of glaucomatous visual field damage in patients with open angle glaucoma, and thus it is helpful in early diagnosis of open angle glaucoma.

关 键 词：DDLS/视乳头损伤分期法 视野损害 青光眼 开角型 相关性 

分 类 号：R775[医药卫生—眼科]