DR-Ⅰ型干眼仪在临床的应用  

The clinical application of DR-I Tearscope Plus

作　　者：宁晓玲[1] 郑志俭[1] 

机构地区：[1]山西省眼科医院,中国山西省太原市030002

出　　处：《国际眼科杂志》2007年第2期534-535,共2页International Eye Science

摘　　要：目的:比较正常人与临床怀疑干眼症患者干眼仪泪膜图象及泪液分泌量的变化。方法:采用日本产DR-I型干眼仪对门诊干眼症患者245例490眼的泪膜脂质层光干涉图象形态进行观察,并与正常组50例100眼进行比较。干眼仪观察结果按5组级别统计,1、2级为正常,3、4、5级为异常,结果进行χ2检验。同时用Schirmer-I法观察患者组泪液分泌量。结果:正常组≤2级的人数百分率为84.1%,明显高于患者组58.2%;正常组≥3级的人数百分率为15.9%,明显低于患者组41.8%,两组比较差异有非常显著性意义(P<0.01)。Schirmer-I实验反应的是泪液的量,而泪膜光干涉图象反应的是泪液的质,两者之间部分有平行关系。结论:DR-I型干眼仪可以客观地反映患者泪膜性状的改变和程度及眼表疾病对泪膜的影响,结合干眼仪检查和Schirmer-I实验可为临床诊断提供参考依据。AIM： To compare the image of lacrimal film and the change of the quantity of tear fluid between normal population and clinically suspected xerophthalmia patients. METHODS： The lipid layer interference patterns of the lacrimal film of 245 clinical cases （490 eyes） using DR-Ⅰ Tearscope Plus （Japan） were reviewed and compared with 50 control cases （100 eyes）. The result from the DR-Ⅰ Tearscope Plus was divided into 5 grades： grades Ⅰ and Ⅱ were considered normal and grade Ⅲ,Ⅳ and Ⅴ were considered abnormal. At the mean time the quantity of tear fluid secretion in the clinical suspected group was observed with Schirmer-Ⅰ method. RESULT： In the control group 84.1% eyes were found to be ≤grade Ⅱ, significantly more than those in the clinical suspected group 58.2%; and 15.9% of the control group were 〉 grade Ⅲ, significantly fewer than those in the clinically suspected group 41.8%. The difference between the two groups were significant （P 〈0.01）. There is partly parallel relation between DR-Ⅰ Tearscope Plus examination and schirmer-Ⅰ method. CONCLUSION： DR-Ⅰ Tearscope Plus can be a good tool to objectively reflect the characteristic change and its extent of the tear film and to show the influence of the tear film by the ocular surface disease. The combination of DR-Ⅰ Tearscope Plus and Schirmer-Ⅰ method can provide a valuable reference for the clinical diagnosis.　

关 键 词：干眼仪 干眼症 临床应用 泪膜图象 泪液分泌量 

分 类 号：R777.2[医药卫生—眼科]