镍铬及钴铬合金材料表面改性对细菌黏附的影响  

An in vitro study of influence of TiN coat on Ni-Cr、Co-Cr alloy on adhesion of bacteria

作　　者：谢俞霁[1] 韩栋伟[1] 

机构地区：[1]同济大学附属口腔医院修复科,上海200072

出　　处：《同济大学学报（医学版）》2007年第2期34-37,共4页Journal of Tongji University(Medical Science)

基　　金：国家自然科学基金资助项目(30670570)

摘　　要：目的研究临床用镍铬合金、钴铬合金表面氮化钛膜对合金表面细菌黏附能力的影响。方法制作镍铬、钴铬合金各144件,随机各选出72件,采用多弧离子镀法在其表面沉积黏氮化钛膜,未镀膜组为对照组,镀膜组为实验组。在镍铬合金对照组和实验组表面附黏性放线菌和内氏放线菌,在钴铬合金对照组和实验组表面黏附变形链球菌和奈瑟菌。黏附时间为24、48、72 h,每个时间段各24个试件。用菌落形成单位计数法统计分析氮化钛膜形成前后各组细菌的黏附量。结果在细菌黏附24、487、2 h,上述四种细菌在实验组表面黏附量较对照组表面黏附量均显著减少,差别有统计学意义(P<0.01);结论镍铬、钴铬合金表面氮化钛膜可抑制细菌黏附.Objective To study the influence of TiN coat on clinically used Ni-Cr,Co-Cr alloy on adhesion of bacteria. Methods One hundred forty-four pieces of Ni-Cr alloy and One hundred forty-four pieces of Co-Cr alloy were made, and randomly chosen half of them, and then TiN coating was coated on the surface of them by multi-arc TiN coating technique served as experimental group, while those of non-coated, as control, , Definite amounts of Actinomyces naeslundii and Actinomyces viscosus were adhered onto the surfaces of Ni-Cr alloy and TiN/Ni-cr alloy respectively; and definite number of Neisseria and S. mutans were adhered to Co-Cr alloy and TiN/Co-Cr alloy respectively. Number of bacteria was counted at adhesion period 24,48,72 h respectively, Resuits At each period TiN coated Ni-Cr alloy significantly reduced the quantity of Actinomyces naeslundii and Actinomyces viscosus adhered to them（ P 〈 0.01 ） ; TiN coated Co-Cr alloy significantly reduced the quantity of Neisseria and S. mutans adhered to them （P〈0. 01 ）, Conclusion TiN coating may reduce bacterium adhesion on Ni-Cr, Co-Cr alloy,

关 键 词：镍铬合金 钴铬合金 氮化钛镀膜 细菌黏附 牙科 修复材料 

分 类 号：R781[医药卫生—口腔医学]