普外科311例围手术期抗菌药物应用调查  

Survey in 311 Cases of Antibiotics Use During Perioperative PeriodGeneral Surgery

作　　者：赵丽霞　[1] 刘安昌[1] 

机构地区：[1]山东大学齐鲁医院药剂科,山东济南250012

出　　处：《中国现代普通外科进展》2007年第2期167-170,共4页Chinese Journal of Current Advances in General Surgery

摘　　要：目的:调查普外科围手术期抗菌药物应用现状,探讨抗菌药物的合理应用。方法:对311例普外科患者围手术期抗菌药物应用进行回顾性分析。结果:308例患者使用了抗菌药物,预防用药的给药时机在术前2h内的占65.0%,术后预防用药占99.0%;喹诺酮类药物使用率最高,其次是硝基咪唑类、三代头孢菌素类;术后单用、二联、三联应用抗菌药物的比例分别为64.3%,37.4%,1.0%,手术后24.4%的患者用药时间>7d。结论:普外科普遍采用抗菌药物预防手术感染,但严格按围手术期预防用药原则应用者少,必须加强抗菌药物围手术期应用的管理。Objective：To discuss the situation and the rationality of antibiotics use in general surgery during perioperative period. Method：311 cases of patients used antibiotics during Perioperative period was retrospectively analyzed. Results： Antibiotics was used in 308 patients. Of all antibiotics used, 202 patients received antibiotics in two hours before the operation. Quinolones were used most frequently, nitroimidazoles were the second, then were cephalosporins. 64.3% of patients received single antibiotics treatment, and 37.4% and 1.0% of all patients received 2 and 3 kinds of antibiotics combined therapy respectively. 24.4% of the patients were treated with antibiotics formore than 7 days. Conclusions：It is common that antibiotics are used to prophylacte surgical infection in general surgery. It is important to strengthen the management of antibiotics use during perioperative period.

关 键 词：外科手术 抗生素类 围手术期 

分 类 号：R63[医药卫生—外科学] R978.1[医药卫生—临床医学]