氙CT脑血流成像在颞浅动脉-大脑中动脉搭桥术中的应用价值  

Application value of xenon CT cerebral blood flow imaging in STA-MCA bypass surgery

作　　者：张苗[1] 卢洁[1] 李坤成[1] 高艳[1] 殷敬喜[1] 焦力群[2] 李萌[2] 

机构地区：[1]首都医科大学宣武医院医学影像学部放射科,北京100053 [2]首都医科大学神经外科,北京100053

出　　处：《医学影像学杂志》2007年第4期329-332,共4页Journal of Medical Imaging

摘　　要：目的:探讨氙CT脑血流成像评价缺血性脑血管病颅内外血管搭桥术的价值。方法:10例颈内/大脑中动脉闭塞患者实施颞浅动脉-大脑中动脉搭桥术前、术后均行氙CT检查,其中8例于术前行乙酰唑胺负荷试验。对药物负荷前后以及手术前后脑血流量(CBF)进行定性和定量比较分析。结果:10例患者术前病变侧CBF均有降低,行乙酰唑胺负荷试验的8例患者用药后4例CBF降低更明显,其余4例CBF无明显变化或仅轻度增加。术后复查氙CT有8例患者CBF较术前增加,2例CBF较术前降低,手术前后病变区CBF值有显著性差异(P<0.05)。结论:氙CT脑血流成像能够定性、定量评价颈内/大脑中动脉闭塞的脑血流情况和脑血管储备能力,对指导颅内外血管搭桥术和评价疗效具有重要价值。Objective： To evaluate the value of XeCT cerebral blood flow（CBF） imaging in extracranial-intracranial arterial bypass surgery in patients with ischemic cerebrovascular disease. Methods： XeCT was performed on 10 patients with ICA/MCA occlusion before and after STA-MCA bypass surgery. Acetazolamide test was performed on 8 patients before surgery. The CBF was measured, the qualitative and quantitative analysis were carried out before and after surgery and acetazolamide test. Results： The decreased CBF on affected side was found in 10 patients. In 8 patients performed acetazolamide test, CBF decreased more significandy in 4 cases and had no obvious changes in 4 cases after the administration of acetazolamide. In 10 patients, the value of CBF significandy increased in 8 cases and decreased in 2 cases after surgery. There was statistically significant difference between the value of CBF before and after surgery （ P 〈 0.05）. Conclusion：XeCT could provide measurement of CBF and vascular reserve capacity in patients with ICA/MCA occlusion, and plays an important role in selecting indication and evaluating effect of extracranial-intracranial arterial bypass surgery.

关 键 词：氙 体层摄影术 X线计算机 脑血流 脑血管重建术 

分 类 号：R743[医药卫生—神经病学与精神病学] R814.42[医药卫生—临床医学]