颅内星形细胞瘤的磁共振波谱分析  

MR SPECTROSCOPY ANALYSIS OF ASTROCYTOMA

作　　者：高阳[1] 牛广明[1] 韩晓东[1] 

机构地区：[1]内蒙古医学院附属医院磁共振室,内蒙古呼和浩特010050

出　　处：《内蒙古医学院学报》2007年第2期84-87,共4页Acta Academiae Medicinae Neimongol

摘　　要：目的：应用磁共振波谱（MRS）成像,对各种代谢产物比值在术前评价星形细胞瘤组织学分级中的价值.方法：41例经病理组织学证实的星形细胞瘤,均在常规MR扫描后,进行MRS成像及普通增强扫描.获得代谢产物曲线,利用分析软件包（function-tool）计算NAA/Cr,Ch/Cr,NAA/Ch,进行统计学分析.结果：高度恶性星形细胞瘤（21例）NAA/Cr,Ch/Cr,NAA/Ch值分别为0.68±0.25（0.24～1.23）、4.87±1.89（2.33～7.99）及0.18±0.11（0.06～0.47）.低度恶性星形细胞瘤（20例）NNA/Cr,Ch/Cr,NAA/Ch值分别为0.97±0.42（0.46～2.30）、2.36±1.22（1.14～6.38）及0.45±0.36（0.16～1.71）.结论：MRS对星形细胞瘤术前分级具有重要价值.Objective：To evaluate the potential of NAA/Cr, Ch/Cr, NAA/Ch in preoperative assessment of histologic grading of astrocytoma by magnetic resonance spectroscopy. Methods. MR imaging was performed by MRS in 41 patients with astrocytoma proven by pathology to obtain NAA/Cr, Ch/Cr and NAA/Ch through function - tool. Results. NAA/Cr, Ch/Cr and NAA/Ch in high - grade astroeytoma （ n = 21 ） were 0. 68 ± 0. 25 （0. 24 - 1.23 ） ,4. 87 ± 1.89 （2. 33 - 7. 99） and 0. 18 ± 0. 11 （0. 06 - 0. 47 ）, and in low - grade astrocytoma （ n = 20 ） were 0. 97 ± 0. 42 （0. 46 - 2. 30 ）, 2. 36 ± 1.22（1.14 -6. 38） and 0. 45 ± 0. 36（0. 16 - 1.71 ） respectively. Conclusion. MRS is very useful in preoperatively predicting tumor grade of astrocytoma.

关 键 词：磁共振 波谱成像 星形细胞瘤 

分 类 号：R739.41[医药卫生—肿瘤]