原发性肝癌伴癌综合征患者糖代谢异常的临床特征  

Clinical feature of abnormal glucose metabolism in the patients with paraneoplastic syndrome of primary hepatic carcinoma

作　　者：钱亦平 黄小勇 

机构地区：[1]浙江省宁波市北仑柴桥医院,宁波315809

出　　处：《临床医学》2007年第4期16-17,共2页Clinical Medicine

摘　　要：目的探讨原发性肝癌(PHC)伴癌综合征(PNS)患者的糖代谢异常的临床特征。方法对确诊的36例PHC伴PNS的患者及36例正常对照组健康者进行口服葡萄糖耐量试验(OGTT)。同时,对36例PHC伴和不伴PNS的患者临床资料进行比较。结果PHC伴PNS患者的血糖呈现空腹血糖偏低,口服75 g葡萄糖后上升缓慢,达到高峰后迅速下降特征。结论PHC伴PNS患者的糖代谢呈现空腹血糖偏低,餐后血糖高峰延迟现象;PHC的患者糖代谢紊乱与Ch ild-Pugh积分、肿瘤大小及AFP值呈正相关。Objective To explore the clinical feature of abnormal glucose metabolism in the patients with paraneoplastic syndrome（PNS） of primary hepatic carcinoma（PHC）. Methods The oral glucose tolerance test（OGTT） was performed in 36 cases of PHC patients with PNS and 36 healthy people in the control group. Meanwhile ,the clinical data of two groups were compared. Results The fasting blood glucose（FBG） of PHC patients with PNS was lower and the blood glucose rose slowly after 75 g oral glucose,declining rapidly following climax. Conclusion The glucose metabolism of PHC patients with PNS have the manifesta- tion of lower FBG and climax retardation of after meal blood sugar, and the disturbance of glucose metabolism in the PHC patients is positively related to Child - Pugh score, the tumor size and the value of AFP.

关 键 词：原发性肝癌 伴癌综合征 糖代谢异常 临床特征 

分 类 号：R735.7[医药卫生—肿瘤] R587.1[医药卫生—临床医学]