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作 者:张智风[1] 侯振山[1] 徐东文[1] 徐栓红[1] 丁丽霞[1]
机构地区:[1]郑州市第三人民医院耳鼻咽喉科,河南郑州450000
出 处:《肿瘤基础与临床》2007年第3期260-261,共2页journal of basic and clinical oncology
摘 要:目的探讨喉癌、下咽癌全喉切除术后气管造瘘口复发癌病因、诊断、治疗及预防措施。方法回顾性分析14例喉癌、下咽癌全喉切除术后气管造口复发癌临床资料,对比手术与非手术治疗的效果。结果14例气管造口复发癌患者全喉切除术前8例有气管切开(8/14)。手术治疗8例,术后生存4-62个月,平均29.8个月;非手术治疗5例,术后生存3-8个月,手术可延长生命(P〈0.01)。结论气管造口复发癌的病因可能与术前气管切开有关;全喉手术中肿瘤的彻底切除,术中快速冰冻监控,气管旁淋巴结清扫是降低本病发生率的重要保证。Objective To study the etiopathology, diagnosis , management and prevention of peristomal recurrence after laryngectomy. Methods Retrospective analysis of clinical management and outcomes of 14 cases of peristomal recurrence. Results Tracheotomy before laryngectomy may result in peristomal recurrence. The survival period of 8 cases surgically treated was longer than that of 5 cases irradiatedor untreated. Conclusions Surgical management would improve the survival, but overall prognosis is dismal and attention should be focused on prevention. It is evident that early diagnosis of stomal recurrences will yield good results.
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