蛋白质组学在乳腺癌研究中的应用  

Application of proteomics in breast cancer research

作　　者：王星辉（综述）[1] 孙保存（审校）[1] 

机构地区：[1]天津医科大学肿瘤研究所天津医科大学病理教研室,300060

出　　处：《国际肿瘤学杂志》2007年第5期355-358,共4页Journal of International Oncology

摘　　要：蛋白质组学在肿瘤研究中的应用是近几年的研究热点，许多新方法也不断应用于蛋白质组学的研究中，包括组织芯片、蛋白质芯片、差异显示双相凝胶电泳以及最新的表面增强激光解析电离飞行时间质谱（SELDI-TOF-MS）蛋白质芯片技术，这些新方法在乳腺癌的早期诊断、预后评价以及信号转导等方面都取得一定进展。Proteomics becomes the focus of cancer research in resent years. Many new methods are applied in proteomics, including tissue microarray, protein microarray, differential in-gel electrophoresis and surface-enhanced laser desorption/ionization-time of flight mass spectrometry. Recently, they are applied to the study of breast cancer for the early diagnosis, prognosis and prediction of treatment outcome as well as signal pathway profiling.

关 键 词：蛋白质类 乳腺肿瘤 蛋白质芯片 

分 类 号：R737.9[医药卫生—肿瘤]