老年脑梗死患者血清及脑脊液中C-反应蛋白的水平及临床意义  

The Level and Clinical Significance of C-Reactive Protein in the Serum and Cerebrospinal Fluid in Elderly Patients with Cerebral Infarction

作　　者：郑学军[1] 冯冬梅[2] 张万森[1] 张斌[3] 阮海玲[1] 王翠兰[1] 

机构地区：[1]河北北方学院附属第一医院老年病科,河北张家口075000 [2]河北北方学院附属第一医院皮肤科,河北张家口075000 [3]河北北方学院附属第一医院检验科,河北张家口075000

出　　处：《河北北方学院学报（医学版）》2007年第2期33-34,共2页Journal of Hebei North University:Medical Edition

基　　金：张家口市科学技术研究与发展指导计划项目(编号:050115)

摘　　要：目的:探讨老年脑梗死患者血清和脑脊液(CSF)中C-反应蛋白(CRP)的水平及临床意义。方法:对20例老年脑梗死患者进行血清和CSF中CRP的检测,分析血清CRP与CSF CRP的相关性。结果:直线相关分析显示,血清CRP与CSF CRP水平呈正相关(r=0.9606,P=0.01)。结论:老年脑梗死患者CSF出现CRP的基础可能是血脑屏障受损。Objective： To investigate the level and clinical significance of C-Reactive Protein（CRP）in serum and cerebrospinal fluid（CSF）in elderly patients with cerebral infarction. Methods： Twenty elderly patients with cerebral infarction received the detections of CRP in serum and CSF. The contents of CRP in serum and that in CSF were detected,and the correlations between CRP in serum and that in CSF were analyzed. Resuits：Linear correlation analysis showed CRP in serum was significantly and positively correlated with that in CSF（r= 0. 9606, P=0.01）. Conclusion：Possibly,there exists CRP in CSF of elderly patients with cerebral infarction because of their blood-cerebral barriers impaired.

关 键 词：脑梗死 CRP 血清 脑脊液 

分 类 号：R743[医药卫生—神经病学与精神病学]