乳腺癌活检方法与预后关系的分析  

Ralationship between the way of biopsy of breast cancer and its prognosis

作　　者：朱世光[1] 于同虎[1] 乔广东[1] 苏海龙[1] 李刚[1] 

机构地区：[1]青岛大学医学院附属烟台毓璜顶医院肿瘤外科,山东烟台264000

出　　处：《中华肿瘤防治杂志》2007年第9期712-713,共2页Chinese Journal of Cancer Prevention and Treatment

摘　　要：为了探讨乳腺癌活检方法对预后的影响,总结330例行术前活检的原发性乳腺癌病例,对活检方法及肿瘤残留与预后的关系进行分析。结果:活检非延迟组、活检延迟组和针吸活检组的复发率分别为10.0%(15/150)、16.3%(13/80)和12.0%(12/100)。活检延迟组中的切取活检组复发率为38.9%(7/18),与其他各组之间差异有统计学意义,P值分别为0.001、0.037和0.011;在伴有间质浸润的癌残留病例中复发率明显增高(43.8%)。切取活检延迟组在无瘤生存率及总生存率方面与活检非延迟组之间差异有统计学意义(P=0.002、0.025),特别是活检距根治手术的时间>7d者。初步研究结果提示,活检距根治手术的时间最好在1周内进行,切除活检和针吸活检者预后好,切除活检时应避免有间质浸润的癌残留。The ojective of this study was to investigate the way of biopsy and its prognosis in patients with breast cancer. The data of 330 cases of primary breast cancer with biopsy were summarized. The way of biopsy, the remains of tumor and their ralationship with the prognosis were analysed. The recurrence rates of patients without de lay after biopsy, with delay after biopsy and with fine needle aspiration biopsy were 10.0% （15/150）, 16.3% （13/80） and 12.0 % （12/100）, respectively. The recurrence rate of patients with incisional biopsy was 38.9 % （7/18）, which was higher than those of the others （P= 0. 001,0. 037,0.011 ）, especially in the patients with remains and interstitial infiltration of tumor. The disease free survival and overall survival of patients with delay after incisional biopsy were worse than those of the patients without delay, particularly the delay time before mastectomy was longer than one week. In conclusion, the time before mastectomy should be no longer than one week after the biopsy of breast cancer. Excisional biopsy and fine-needle as piration biopsy are the best ways of all, and the remains and interstitial infiltration of tumor must be avoided in the case of exeisional biopsy.

关 键 词：乳腺肿瘤/病理学 活组织检查 预后 

分 类 号：R737.9[医药卫生—肿瘤]