A 9-year-old Chinese boy with Alagille syndrome  

作　　者：HUANG Xiao-lei CHEN Jie MA Ming WANG Pei-xin 

机构地区：[1]Department of Gastroenterology, Children＇s Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

出　　处：《Chinese Medical Journal》2007年第10期941-942,共2页中华医学杂志（英文版）

摘　　要：Alagille syndrome （AGS, OMIM#118450） is a multi-system, autosomal dominant disorder with variable clinical manifestation, which primarily affects the liver, heart, eyes, face, and skeleton. The estimated incidence of AGS is 1 in 70000 births of all races worldwide; however it has been rarely reported in Chinese children. We treated a Chinese boy presenting with jaundice, pruritus and gowth failure finally who had been diagnosed as having AGS. Informed consent was obtained from the legal guardian of the child before reporting.Alagille syndrome （AGS, OMIM#118450） is a multi-system, autosomal dominant disorder with variable clinical manifestation, which primarily affects the liver, heart, eyes, face, and skeleton. The estimated incidence of AGS is 1 in 70000 births of all races worldwide; however it has been rarely reported in Chinese children. We treated a Chinese boy presenting with jaundice, pruritus and gowth failure finally who had been diagnosed as having AGS. Informed consent was obtained from the legal guardian of the child before reporting.

关 键 词：Alagille syndrome CHOLESTASIS GROWTH 

分 类 号：R596[医药卫生—内科学]