鲜鱼腥草酚类化学成分的研究  

Studies on chemical constituents of phenols in fresh Houttuynia cordata

作　　者：孟江[1] 董晓萍[2] 周毅生[1] 姜志宏[3] 梁士贤[3] 赵中振[3] 

机构地区：[1]广东药学院中药学院,广东广州510000 [2]成都中医药大学药学院,四川成都610000 [3]香港浸会大学中医药学院

出　　处：《中国中药杂志》2007年第10期929-931,共3页China Journal of Chinese Materia Medica

摘　　要：目的:研究三白草科Saururaceae蕺菜属植物蕺菜Houttuynia cordata的酚类化学成分。方法:利用Diaion HP-20,Sephadex LH-20,ODS和硅胶柱色谱进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果:分离得到5个化合物,分别鉴定为:绿原酸甲酯(1),4-羟基-4[3′-(β-D-葡萄糖)亚丁基]-3,5,5-三甲基-2-环己稀-1-醇(2),2-(3,4二羟基)-苯乙基-β-D-葡萄糖苷(3),对羟基苯乙醇-β-D-葡萄糖苷(4),4-β-D-葡萄糖-3-羟基苯甲酸(5)。结论:该5个化合物均为首次从该属及本植物中分离得到。Objective： To study the aqueous constituents of Houttuynia cordata. Method： Various columns including Diaion HP-20, Sephadex LH-20, ODS and silica gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis. Result： Five compounds were isolated, and their structures were identified as chlorogenic methyl ester （ 1 ）, （E） -4-Hydroxy-4-[ 3＇-（β-D-glucopyranosyloxy） butylidene] -3, 5, 5-trimethyl-2-cyclohexen-1-one （2）, 2- （ 3, 4-dihydroxyphenyl） ethyl-β-D-glucopyranoside （3）, p-hydroxyphenethyl-β-D-glucoside （4）, 4-（β-D-glucopyranosyloxy）-3-hydroxy-Benzoic acid （5）. Conclusion： All compounds were isolated from this plant for the first time.

关 键 词：鲜鱼腥草 化学成分 酚类 

分 类 号：R284.1[医药卫生—中药学]