功能性消化不良患者胃电图与胃排空关系研究  

The investigation of relationship between electrogastrogram and gastric emptying in patients with functional dyspepsia

作　　者：马刚[1] 林琳[1] 张红杰[1] 王美峰[1] 姜柳琴[1] 朱芬芬[1] 

机构地区：[1]南京医科大学第一附属医院消化科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2007年第5期463-466,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省"135工程"重点人才基金项目(RC2003087);江苏省自然科学基金项目(BK2004158)

摘　　要：目的:探讨功能性消化不良患者的胃电图异常与胃排空的相关性。方法:使用PolygrafID四导胃电分析系统和不透X线标志物法测定51例功能性消化不良(FD)患者的胃电活动和餐后5h的胃排空情况。结果:FD患者排空异常占31.4%,胃电异常占72.6%。胃电正常的患者与胃电异常的胃排空率差异无显著性。患者胃排空和胃电图异常时,胃电图节律紊乱,主频正常,部分患者合并餐后主功率不增加。轻度、中度及重度者胃排空率无明显差异;胃电异常率重度者较轻度、中度者明显增高(P<0.05),轻度与中度症状之间、Hp阳性与Hp阴性的胃排空率差异均无显著性,Hp阳性的胃电异常率高于Hp阴性(P<0.05)。有或无活动性胃炎的胃电异常率及胃排空率无显著差异。结论:胃电异常在FD的发病中有一定意义;胃排空延缓与胃电异常无明显联系;重度症状患者和Hp阳性患者胃电异常率明显增高;胃炎有无活动性与胃电图及胃排空无明显相关性。Objective：To investigate the correlations between electrogastrogram（EGG） and gastric emptying（GE） in patients with functional dyspepsia（FD）. Methods： Fifty-one patients with FD were detected by polygraph ID 4-channel EGG analysis system（EGG） and solid radiopaque marker 5h after a solid meal （GE）. Results：31.4% patients with FD showed delayed GE, 72.6% showed abnormal EGG. There were no significant differences between normal EGG groups and abnormal EGG groups in average percentage of postprandial 5 h emptying. In patients who had both abnormal EGG and delayed GE, EGG abnormility mainly exhibited dysrhythmia, and the dominant frequency of EGG were normal. Some patients also exhibited non-enhancive dominant power postprandial. There were no significant differences among patients with mild, moderate and severe symptoms in GE percentage. The patients with severe symptoms had higher dysrhythmia percentage than those in mild and moderate symptoms （P 〈 0.05）, but there was no significant difference between the patients with mild and moderate symptoms. There were no significant difference of GE percentage between Hp negative groups and Hp positive groups, but the dysrhymia percentage of Hp positive groups was higher than Hp negative groups（P 〈 0.05）. There were also no significant differences between active gastritis group and inactive gastris group in both dysrhymia percentage and GE percentage. Conclusion：The abnormality of EGG plays an important role in the pathogenesis of FD. There was no significant relationship between EGG and GE. The patients with severe symptoms and with Hp positive have higher abnormal EGG percentage. Whether the gastritis is active or not, that was no significant correlation with EGG or GE percentage.

关 键 词：功能性消化不良 胃电图 胃排空 胃功能 

分 类 号：R573.9[医药卫生—消化系统] R444[医药卫生—内科学]