难治性额叶癫的外科治疗  

Surgical Treatment for Intractable Frontal Lobe Epilepsy

作　　者：高翔[1] 王晋阳[2] 钟平[1] 朱国行[2] 江澄川[1] 

机构地区：[1]复旦大学附属华山医院神经外科,200040 [2]复旦大学附属华山医院神经内科,200040

出　　处：《中国临床神经科学》2007年第3期285-287,共3页Chinese Journal of Clinical Neurosciences

摘　　要：目的:探讨额叶癫的外科治疗方法。方法:采用EEG、MRI、PET等方法对66例额叶癫灶定侧、定位,并据此进行手术治疗,术中采用皮质刺激以确定运动皮质。结果:所有患者获得定位,MRI和EEG分别对42例及46例作出定位诊断。66例均接受手术治疗:其中病灶切除+癫灶切除42例;癫灶切除11例;癫灶切除+软脑膜下横切术7例;癫灶切除+胼胝体切开术6例。术后癫控制:满意39例,显著改善15例,良好5例,效差7例。无偏瘫、失语等功能障碍。结论:手术治疗额叶癫可取得较满意疗效,EEG和MRI是主要的定位手段,术中采用皮质电刺激可避免运动功能损伤。To discuss the treatment for intractable frontal lobe epilepsy. Methods. 66 intractable frontal lobe epilepsy patients were surgically treated, the seizure foci were located by EEG, MRI. The cortical stimulation was used to locate the motor cortex. Results All the operations were performed under cortex EEG monitoring, patients had seizure foci resection, patients had foci resection with multiple subarachnoid transaction, patients had foci resection with callosumsectomy. Postoperative follow-up showed. Engel Ⅰ 39 cases, Engel Ⅱ 15 cases, Engel Ⅲ 5 cases, Engel Ⅳ 7 cases. There was no neurological complication. Conclusion ：Frontal lobe could be treated satisfactorily by surgery, EEG and MRI were important in seizure foci localization. Motor and language function should be preserved in operation.

关 键 词：额叶 癫痫 手术 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R656.11[医药卫生—临床医学]