功能性矫治力对青春期恒河猴颅颌骨缝影响的组织学观察  

Histological evaluation of the rhesus monkeys' craniofacial sutures after class Ⅲ functional orthopedics

作　　者：韩秀丽[1] 徐芸[1] 王丽艳[1] 

机构地区：[1]云南昆明医学院第一附属医院口腔正畸科

出　　处：《实用口腔医学杂志》2007年第3期349-352,共4页Journal of Practical Stomatology

基　　金：云南省自然科学基金资助项目(编号:2002C0023R)

摘　　要：目的:探讨早期安氏III类功能性矫治力对上颌骨生长的影响。方法:选6只青春期健康雄性恒河猴,给4只实验组动物(2只为1.5月组,2只为3月组)分别佩戴铸造式双阻板磁力功能矫治器,建立上颌前突、下颌后缩的动物模型,2只对照组动物(1只1.5月组,1只3月组)不佩戴矫治器。分别于1.5月和3月后处死,取上颌骨周围颧颌缝、颧颞缝、颧额缝、额颌缝、腭横缝、翼腭缝区组织,作HE染色,取左侧颧颞缝组织作电镜观察。结果:实验组动物经过III类功能矫形后,上颌骨周围骨缝边缘新骨形成明显,尤其以颧颌缝、颧颞缝、腭横缝为主。电镜下,颧颞缝区组织成骨细胞、成纤维细胞功能活跃,尤其以成纤维细胞为主。对照组动物无上述改变。结论:安氏III类功能性矫治过程中,上颌骨周围骨缝积极改建,骨缝边缘新骨形成活跃。Objective：To detect the influence of the early Class III orthopedic treatment on the development of the maxillary. Methods： Four adolescence rhesus monkeys were fitted with casting Twin-block magnetic appliance （TMA）, two were put to death after 1.5 months and another two after 3 months, zygomaticofrontal sutures were harvested, and performed histological examination using optical and electron microscope. Another two monkeys without appliance were served as control. Results：The maxillary sutures were rebuilt, after Class III functional orthopedic, and the zygomaticomaxillary suture, zygomaticotemporal suture and transverse palatine suture were especially active. Electron microscopy results showed that osteoblasts and fibroblasts were active, and fibroblasts showed more active effects. Conclusion： During the treatment of the Class III functional orthopedics, maxillary sutures take part in the rebuilding actively, and there are lots of new bone formation along the sutures.

关 键 词：Ⅲ类功能矫治 恒河猴 上颌骨周围骨缝 HE染色 电镜 

分 类 号：R783.5[医药卫生—口腔医学]