咽异感症与胃食管反流的关系  

Relationship between globus hystericus and gastroesophageal reflux

作　　者：陈维顺[1] 罗虹雨[1] 张选均[1] 朱宜人[1] 钟燎原[1] 周红兵[1] 周婷[1] 

机构地区：[1]中南大学湘雅医学院株洲临床学院湖南省株洲市一医院消化内科,株洲412000

出　　处：《临床医学》2007年第5期3-4,共2页Clinical Medicine

摘　　要：目的观察咽异感症患者的胃食管反流情况,评估胃食管反流在咽异感症病因学及临床表现中的作用。方法按罗马Ⅱ标准,对26例咽异感症患者进行食管内24 h动态pH和胆汁监测,然后进行7 d的埃索美拉唑(耐信)试验治疗,并选择26例同期年龄、性别相匹配的胃食管反流病患者进行对照。结果观察组发生病理性反流者咽异感症8例(30.8%),对照组17例(65.4%),两组比较差异有统计学意义(P<0.05)。埃索美拉唑治疗后咽异感症7例症状消失,10例症状减轻,有效率65.4%。对照组13例症状消失,9例症状减轻,有效率84.6%。两组比较差异无统计学意义(P>0.05)。结论部分咽异感症患者存在病理性胃食管反流,用抑酸治疗有效,提示病理性胃食管反流可能是咽异感症的病因之一。Objective To observe the gastroesophageal reflux（ GER）in globus hystericus and to investigate the relationship between globus hystericus and GER. Methods Twenty - six patients with globus hystericus（21 women,5 men; mean age 38. 5 years, ranging from 23 to 55 years） and twenty - six patients with gastroesophageal reflux disease （GERD） （22 women,4 men, mean age 37.2 years,range from 22 to 52 years） were studied by using arubulatory pH monitor and bilitic 2000. All patients were evaluated with the therapeutic test of esopmeprazol. Results The abnormal gastroesopbageal reflux were diagnosed in 8 patients（30. 8% ） with globus hystericus and 17 patients（65.4% ） with GERD. The symptoms disappeared or were alleviated in 17 patients（65.4% ） with globus hystericus and 22 patients（84. 6% ） with GERD by the therapeutic test of esopmeprazol. Conclusion A part patients with globus hystericus folow the abnormal gastroesophageal reflux,which cold be one of cause of globus hystericus.

关 键 词：咽异感症 胃食管反流 诊断 治疗 

分 类 号：R571[医药卫生—消化系统]