超临界CO_2流体提取车前子总黄酮的工艺优化  

The CO_2 Supercritical Fluid Extraction Technology of Flavonoids in Semen Plantaginis

作　　者：万茵[1] 谢明勇[1] 董欢欢[1] 周超[1] 

机构地区：[1]南昌大学食品科学教育部重点实验室,江西南昌330047

出　　处：《南昌大学学报（理科版）》2007年第2期160-163,共4页Journal of Nanchang University(Natural Science)

基　　金：长江学者和创新团队发展计划资助项目(IRT0540);江西省科技攻关资助项目(2004)

摘　　要：通过正交实验研究,对超临界CO2流体提取车前子中黄酮类化合物的工艺进行了优化,实验结果表明各因素对总黄酮提取率的影响程度由小到大依次为:提取温度、夹带剂用量、提取压力、提取次数。在提取时间为0.5 h的条件下,最佳提取工艺条件为:提取温度45℃、压力300 Bar、夹带剂无水乙醇用量2.5 mL/g原料、提取2次。The CO2 supercritical fluid extraction technology of flavonoids in Semen Plantaginis was optimized by orthogonal experiments. The experimental results showed that the order of different factors affecting extraction rate was extraction time 〉 extraction pressure 〉 ethanol dosage 〉 extraction temperature. At the condition of 0.5 h extraction time, the optimal experimental parameters were 45 ℃ extraction temperature ,300 Bar extraction pressure,2.5 mL/ （g materials） ethanol dosage, twice. The results showed that the extraction rate of flavonoids was considerable.

关 键 词：超临界CO2流体提取 车前子 总黄酮 

分 类 号：O69[理学—化学] R284.2[医药卫生—中药学]