双根清脑煎剂对血管性痴呆大鼠模型脑海马组织及血清SOD MDA的影响  

Effect of Shuanggenqinnao Jianji on SOD MDA of Hippocampus and Serum in Vascular Dementia Rats

作　　者：蔡建伟[1] 吴颢昕[1] 晋光荣[2] 向红兵[2] 林靓[1] 

机构地区：[1]南京中医药大学,江苏南京210029 [2]东南大学医学院,江苏南京210009

出　　处：《中华中医药学刊》2007年第6期1167-1168,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：江苏省中医药管理局基金资助项目(H013)

摘　　要：采用从颈外动脉进行插管缓慢注入同种血栓栓子造成大鼠血管性痴呆模型。观察双根清脑煎剂及尼莫通对血管痴呆大鼠模型脑海马组织与血清SOD、MDA的影响。结果表明,双根清脑煎剂及尼莫通能显著升高SOD活性,且上调SOD/MDA值。Retrograde injection with the homologous embolus through the external carotid artery initiated the vascular dementia rats. Observed the effect of shuanggenqinnao jianji and nimotop on SOD ＆ MDA of hippocampus and serum in vascular dementia rats. The results showed that both shuanggenqinnao jianji and nimotop could obviously improve the vigour of SOD,and raise the racio of SOD/MDA.

关 键 词：双根清脑煎剂 血管性痴呆 SOD MDA 

分 类 号：R-33[医药卫生]