和胃理肠丸中白术挥发油的提取及包合工艺的研究  

Study on the Technological Process of Extraction and Clathration for Rhizoma Atractylodis Macrocephalae Oil with β-cyclodextrin

作　　者：黄江虹[1] 

机构地区：[1]广州中医药大学第二临床医学院,广东广州510120

出　　处：《中药材》2007年第5期613-616,共4页Journal of Chinese Medicinal Materials

摘　　要：目的:优选和胃理肠丸中白术挥发油的提取工艺及包合工艺。方法:采用正交试验设计,以白术挥发油得率为指标优选提取工艺;以包合物收率及挥发油包合率为指标优选包合工艺,并用薄层色谱法对包合物进行鉴别。结果:优选的提取工艺为白术粗颗粒,加水10倍量,提取6 h;包合物的制备工艺为:β-CD与白术挥发油的投料比为6∶1,加水3.5倍,研磨75 min。结论:提取工艺与包合工艺合理可行,适合工业化生产。Objective ： To study the optimal extraction and clathration technology of Rhizoma Atractylodis Macrocephalae oil in Heweilichang Pill. Methods： Orthogonal test was employed for selecting the optimum of extraction technology of Rhizoma Atractylodis Macrocephalae oil and the oil extraction rate were used as a index. The optimum including technology was chosen by determining the oil-bearing rate and extract ratio of inclusion compound. The inclusion compound were identified with thin chromatogram. Results ： The extraction technology was 10 volumes of water, extracted 6h with thick granula of Rhizoma Atractylodis Macrocephalae. The optimum preparation conditions for clathrate were established as β-CD： oil was 6： 1, 3.5 times of water, triturated for 75 minutes. Conclusion： The process is feasible and the method can be used for production.

关 键 词：和胃理肠丸 正交试验法 白术挥发油 Β-环糊精 

分 类 号：R284.2[医药卫生—中药学]