以人群为基础子宫肌瘤危险因素病例对照研究  

Population-based case-control study on risk factors of uterine myomas

作　　者：王玮[1] 许伟[2] 丁淑玉[3] 周宝森[1] 

机构地区：[1]中国医科大学流行病教研室,辽宁沈阳110001 [2]沈阳市卫生局基妇处,辽宁沈阳110001 [3]沈阳市第七人民医院电诊科,辽宁沈阳110001

出　　处：《中华肿瘤防治杂志》2007年第11期821-823,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的：探讨妇女子宫肌瘤的患病情况及其危险因素。方法：采用分层随机抽样的方法对沈阳地区1260名女性的子宫肌瘤患病状况进行问卷调查,对113例病例采用1∶2配比病例对照研究方法,探讨子宫肌瘤危险因素。结果：子宫肌瘤患病率为8.97%（113/1 260）,其中40-49岁组的患病率最高为15.29%（65/425）;影响子宫肌瘤发生的危险因素按危险性大小依次为月经紊乱、既往盆腔炎、既往宫颈炎、口服避孕药、既往阴道炎和人工流产史,而月经初潮年龄延迟可能是子宫肌瘤的保护因素。结论：子宫肌瘤发病与月经紊乱、既往盆腔炎、既往宫颈炎、既往阴道炎、口服避孕药和人工流产史有关。有必要针对各种危险因素加强女性健康教育,提高其生殖健康水平。OBJECTIVE： To investigate the prevalence of uterine myomas and the risk factors. METHODS.. By using stratified random sampling method, 1 260 women were surveyed by questionnaire, and 1 ： 2 matched case-control study was used to explore the influential factors of uterine myomas. RESULTS： The prevalence of uterine myomas was 8.97% （113/1260）, and the group aged from 40 to 49 had the highest morbidity rate, 15.29 %（65/425）. Risk factors of uterine myomas included： menstrual disorder, pelvic inflammatory, cervicitis, oral contraceptive medication, elytritis, and induced abortion, respectively, while delayed menstruation was proved to be a preventive factor. CONCLUSIONS： Uterine myomas seemed to be related to menstrual disorder, pelvic inflammatory, cervicitis, elytritis, and induced abortion. There is a great need for emphasizing culturally acceptable reproductive health education in various kinds of risk factor to improve women＇s knowledge about uterine myomas.

关 键 词：子宫肿瘤/病因学 平滑肌瘤/病因学 危险因素 病例对照研究 回归分析 

分 类 号：R737.33[医药卫生—肿瘤]