正常有色素家兔眼的视网膜功能研究  

Retinal Function of Healthy Pigmented Rabbits

作　　者：滕岩[1] 宋晗[1] 郑建秋[1] 遇颖[1] 于旭辉[1] 董丽[1] 齐杰[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院眼科医院,哈尔滨150001

出　　处：《中国实验动物学报》2007年第3期198-202,I0004,共6页Acta Laboratorium Animalis Scientia Sinica

基　　金：黑龙江省十五攻关课题(编号:GB02C141-02)

摘　　要：目的通过分析正常有色素家兔的mfERG的特征,了解其视网膜的功能特性。方法对9只兔18眼正常有色素家兔同时检测mfERG,并与正常成人的18只眼的检测结果对照分析。结果正常有色素家兔mfERG的P1波振幅密度三维地形图特点,可见黄斑区高峰,但较人黄斑区高峰为低,其他部分呈颞侧高鼻侧低的斜坡状,象限野mfERG颞侧半可见P1波振幅密度、P1波振幅、N1波振幅比鼻侧增高;也高于正常成人眼的颞侧值。五个环形野mfERG,P1波振幅密度,第1环最大,由1环到5环依次递减,P1和N1波振幅以4环和5环最大;与人相比环1的P1波振幅密度和振幅降低,环4和环5增高。结论兔眼颞侧视网膜功能高于鼻侧。兔眼视网膜存在类人黄斑区,但其黄斑中心视功能不如人眼,中心外视功能高于人眼。Objective To analyze the characteristics of muhifocal electroretinogram （mfERG） of healthy pigmented rabbit eyes, and assess their retinal function. Methods MfERG were performed in 18 eyes of 9 rabbits, and compared with those of 18 human eyes. Results In mfERG the macular peak arose in three-dimensional picture, composed of Pl-wave amplitude density, but is lower than that of humans. In other ports of the retina, the slope composed of higher density in the temporal area and lower in the nasal area. The Pl-wave amplitude density, Pl-wave amplitude value and Nl-wave amplitude value in temporal retina of mfERG are higher than those in nasal retina in the rabbit eyes, and also higher than those in temporal retina in human eyes. In 5 rings mfERG of rabbit eyes, Pl-wave amplitude density in the first ring was the highest and declines from the first ring to 5th ring gradually. Pl-wave and Nl-wave amplitude values in 4th ring and 5th ring were the highest, Pl-wave amplitude density and Pl-wave amplitude value in the first ring were lower than those in human eyes, but higher in 4th and 5th rings. Conclusion The function of temporal retina of rabbit eyes is superior to that of nasal retina. The rabbit retinal function of central macula is inferior to human one, but the function of para-macular area is superior to that of human eves.

关 键 词：兔 多焦视网膜电图 功能 

分 类 号：R774[医药卫生—眼科]