乳香、没药挥发油β-CD包合物的实验研究  

Experimental Study on β -Cyclodextrin Inclusion Compound of Frankincense and Myrrh Essential Oil

作　　者：于维萍[1] 辛义周[1] 

机构地区：[1]山东中医药大学附属医院,济南市250011

出　　处：《中国药房》2007年第18期1379-1381,共3页China Pharmacy

摘　　要：目的:将乳香、没药挥发油制成β-CD包合物,并考察其质量。方法:采用均匀试验法研究β-CD包合工艺;应用薄层色谱、差动热分析和X-射线衍射分析法对包合物进行质量考察。结果:该包合物确已形成一种新的物相,包合前、后挥发油组成无变化。结论:β-CD包合技术可以使乳香、没药挥发油固体化,从而减少挥发损失。OBJECTIVE ： To prepare β-CD inclusion compound of frankincense and myrrh essential oil and to investigate its quality. METHODS： The technique of β-CD inclusion was studied by uniformity experimental design, and the quality of the inclusion compound was investigated by analyses of TCL, DSC （Differential scanning calorimetry） and X-ray diffraction. RESULTS： A new material phase has been formecl in this β-CD inclusion compound, and no change was found in the components of the essential oil after inclusion. CONCLUSION： β-CD inclusion technique can make frankincense and myrrh essential oil solidified, thus decreasing its loss from volatilization.

关 键 词：乳香 没药 挥发油 Β-环糊精 包合物 均匀试验 物相分析 

分 类 号：R943[医药卫生—药剂学] R283[医药卫生—药学]