眼部新生血管与抗血管内皮生长因子治疗  

Anti-vascular endothelial growth factor treatment for ocular neovascularization

作　　者：刘正[1] 王业青[1] 张晓梅[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院附属眼科医院,中国黑龙江省哈尔滨市150001

出　　处：《国际眼科杂志》2007年第3期779-781,共3页International Eye Science

基　　金：中国黑龙江省自然科学基金资助项目(No.D200662)~~

摘　　要：眼部新生血管性病变是致盲的主要原因之一,可见于多种眼底疾病,其确切的发病机制尚不完全清楚。大量的研究证据表明血管内皮生长因子(VEGF)是新生血管形成的关键调控因子。本文对VEGF的特性、VEGF在眼部新生血管形成中的作用和抗VEGF治疗进行综述。Ocular neovascularization is the primary cause of blindness in a wide range of ocular diseases. The exact mechanism underlying the pathogenesis of ocular neovascularization is not yet well understood. There is extensive evidence that vascular endothelial growth factor （VEGF） is a major regulator of neovascularization. The present paper focuses on VEGF and its role in ocular neovascularization and current anti-VEGF treatment.

关 键 词：新生血管 血管内皮生长因子 治疗 

分 类 号：R77[医药卫生—眼科]