米氮平与阿咪替林治疗抑郁、焦虑的对照研究  

Comparative Study of Mirtazapine vs Amitriptyline in Treatment of Depressive and Anxiety Patients

作　　者：薛慧英[1] 

机构地区：[1]沈阳医学院沈洲心理卫生医院,110032

出　　处：《中国健康心理学杂志》2007年第6期490-492,共3页China Journal of Health Psychology

摘　　要：目的探讨米氮平和阿咪替林在治疗抑郁焦虑方面的疗效与副反应。方法将65例焦虑和抑郁患者随机分为米氮平组和阿咪替林组治疗8周。应用汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)及治疗副反应量表(TESS)测查治疗前后的疗效及副反应。结果二者疗效无显著性差异,米氮平组的副反应发生百分率低于阿咪替林组。结论米氮平和阿咪替林在治疗焦虑抑郁方面疗效相当,米氮平毒副反应明显低于阿咪替林。Objective To compare the efficacy and side effects of mirtazapine and amitriptyline in the treatment of depressive and anxiety patients. Methods 65 depressive and anxiety patients with depression and anxiety were randomly divided into mirtazapine group or amitriptyline group for 8 weeks respectively. The efficacy and side effects were evaluated by HAMD snd HAMA and TESS. Results The efficacy was no significant difference between two groups. The side effective rates of mirtazapine group was lower than that of amitriptyline groups. Conclusion Mirtazapine has the same efficacy with amitriptyline. The side effective of mirtazapine was lower significant than that of amitriptyline groups.

关 键 词：米氮平 阿咪替林 抑郁 焦虑 

分 类 号：R749.4[医药卫生—神经病学与精神病学]