六味洗剂的质量标准研究  

The Study on Quality Standards of Liuwei Lotion

作　　者：张爱军[1] 张薇 李兴华[1] 王香兰[1] 

机构地区：[1]西安交通大学医学院第二附属医院,陕西西安710004 [2]西安电力医院,陕西西安710032

出　　处：《中国实验方剂学杂志》2007年第6期7-9,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：西安市科技计划项目(SF200238)

摘　　要：目的:制定六味洗剂的质量控制标准。方法:采用薄层层析法鉴别处方诸药,反相高效液相法测定没食子酸含量。结果:没食子酸浓度在0.16～0.64μg/mL范围内与吸收峰面积线性关系良好,标准曲线为Y=-16 887.5X+418 327,r=0.999 7,平均回收率为99.45%,RSD=1.12%。结论:六味洗剂质量控制方法准确可靠,分离度好。Objective：To formulate the quality standard of Liuwei Lotion. Methods： Thin layer chromatography （TLC） was used to identified the each herbal in the lotion. Gallic acid concentration was measured by RP-HPLC. Resul： The concentration of gallic acid ranging from 0.16 to 0.64 μg/mL, showed good linear relation with the peak area. The standard curve was Y= - 16 887.5X ＋418 327, r = 0.999 7. The average recovery was 99.45%, RSD = 1.12%. Conclusion： The methods of quality control were accurate and reliable.

关 键 词：六味洗剂 没食子酸 质量标准 

分 类 号：R283.6[医药卫生—中药学]