二极管睫状体光凝治疗新生血管性青光眼两种方案比较  

Diode Laser Transscleral Cyclophotocoagulation for Neovascular Glaucoma:A Comparison of Two Treatment Protocols

作　　者：杨士强[1] 蔡鸿英[1] 张金华[1] 

机构地区：[1]天津市眼科医院,300020

出　　处：《天津医药》2007年第6期427-429,共3页Tianjin Medical Journal

摘　　要：目的:评价二极管激光经巩膜睫状体光凝治疗难治性新生血管性青光眼的2种治疗方案的有效性和安全性。方法:对88例新生血管性青光眼患者按就诊时间分为2组分别给予不同方案治疗,A组60眼每个激光点的持续时间2000ms,治疗点数是(21.43±3.38)点(20～34点)。B组28眼每个激光点的持续时间2000ms,治疗点数是(55.46±9.13)点(40～72点)。分别记录术前术后24h眼压、视力、症状、用药以及角膜、虹膜、前房和晶状体等情况,随访1年的眼压、用药情况并进行统计比较。结果:2组眼压较术前均有下降,A组眼压下降幅度为18.78mmHg,B组眼压下降幅度为28.10mmHg,2组差异有统计学意义(P<0.01)。并发症B组短期前房炎症反应较重,经局部药物治疗后缓解,其他如前房出血、角膜水肿、视力下降2组差异无统计学意义(P>0.05)。结论:接触式二极管激光经巩膜睫状体光凝治疗难治性新生血管性青光眼是有效的,其中,治疗点数多的比治疗点数少的更有效,且是安全的。Objective： To evaluate the efficacy and safety of two treatment protocols of diode laser transscleral cyclophotocoagulation （TDLC） for neovascular glaucoma. Methods： Eighty-eight cases of neovascular glaucoma were treated with TDLC performed according to two different protocols. Before and after 24 h treatment, the intraocular pressure （IOP）, SneUen visual acuity, the number of antiglaucoma medications and slit-lamp biomicroscopic findings were recorded. The follow-up period was 1 year. Results： After operation, both short-term and long-term IOP were significantly lower than those before operation in two groups（18.78 mm Hg and 28.10 mm Hg, P 〈 0.01）. The treatment of protocol 2 was more effective than that of protocol 1 （P = 0.019）. There were no significant differences in complications and visual acuity changes. Conclusion： TDLC is an effective method for neovascular glaucoma. The treatment of protocol 2 was more effective and safe compared to those of protocol 1.

关 键 词：青光眼 新生血管性 睫状体 巩膜 激光凝固术 

分 类 号：R775.05[医药卫生—眼科]