射频热凝术治疗顽固性癌性神经痛的临床研究  

THE ROLE OF RADIOFREQUENCY IN THE TREATMENT OF PATIENTS WITH NEUROPATHIC CANCER PAIN

作　　者：李晓宏[1] 赵伟成[1] 王汉兵[1] 闫哲[1] 富沛勇[1] 杨承祥[1] 

机构地区：[1]中山大学附属佛山医院疼痛治疗中心,佛山528000

出　　处：《中国疼痛医学杂志》2007年第3期140-143,共4页Chinese Journal of Pain Medicine

基　　金：佛山市科委立项课题(200404-14)

摘　　要：目的:探讨射频热凝术用于治疗癌性神经痛的疗效及安全性。方法:42例癌性神经痛患者,A组患者(n=20)按三阶梯疗法,采用吗啡药物治疗,B组患者(n=22)在吗啡加用局麻下行射频温控热凝毁损治疗。分别就治疗后疗效、生活质量改善情况及安全性进行评估。结果:B组患者在不同治疗时期的总有效率明显高于A组(P<0.05),生活质量的改善较A组有显著性差异,副作用的发生率较A组低。结论:射频热凝治疗癌性神经痛是一种安全有效的微创介入治疗方法。Objective：To investigate the efficacy and safety of radiofrequency in the treatment of neuropathic cancer pain. Methods： 42 cases of cancer patients who had failed to relief pain with Diclofenac and anticonvulsants were divided into two groups randomly and treated by morphine （group A, n = 20） and morphine combined with radiofrequency （group B, n = 22） respectively. The total consumption of the antalgesic and quality of life were observed to evaluate efficacy and safety of these drugs. Results： The total efficiency in group B was significandy higher than that in group A （ P 〈 0.05 ）, and there were more improvements in life quality of patients and less side effects in group B than that in group A. Conclusion： Radiofrequency can be used in treating the neuropathic cancer pain efficiendy and safely.

关 键 词：射频热凝 神经源性疼痛 癌症 

分 类 号：R730.5[医药卫生—肿瘤]