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机构地区:[1]河南省肿瘤医院麻醉科
出 处:《河南肿瘤学杂志》1997年第2期108-109,共2页Henan Journal of Oncology
摘 要:50例肿瘤伴高血压病人,男30例,女对例,年龄60~70岁,随机分为两组。两组均采用硝酸甘油(NTG)5mg,注药方法不同。I组经鼻腔间断滴人,Ⅱ组静脉滴入。结果显示:I组注NTG后,平均动脉压(AIAll、心率(HR)与前一时间相比P<0.01。Ⅱ组注NTG后MAP、HR与前一时间相比P<0.05和P<0.01,两组注药前后SOP2无明显变化。50例病人中有叨例术前心电图(ECG)异常,注NTIY;后至手术结束有明显好转。我们采用不同方法,均达到降压效果。但是,Ⅱ组降压迅速、不稳定,I组降压缓和、平稳。Fifty Patients were randomly divided into two groups, their ages ranged from 60~70 years old,30cases were male and 200 cases female. In either group 5mg NTG was used,but in different ways. In groupI NTG was intermittently droppen in nostrils.In group II NTG was dripped into veins.The results showedthat bafore and after injechon on beth groups there was significant statistical difference in the MAP(meanarterial pressure) and HR (heart rate) in group I (P <0.01),in group II (P <0.05 and P <0.01).In both groups SPO2(Pulse oxygen saturation) was satisfactory. In 30 out of 5O cases, the ECG was abnor-mal before operation,but became satisfastory ther infusion of NTG till the end of operation. Remarkableeffect on reducing blood pressure was gained in different ways but in group II pressure was reducedrapidly,but instably, in group I pressure was reduced slowly and stably.
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