聚对羟基苯乙烯单体的中间体——对特丁氧酰氧基苯乙烯合成方法的改进  

Synthetic Improvement of p-tert-Butoxycarbonyloxystyrene—Intermediate of Monomer of Poly(p-Hydroxystyrene)

作　　者：刘建国[1] 李平[1] 李萍 郑家燊[1] 

机构地区：[1]华中科技大学化学系,武汉430074

出　　处：《应用化学》2007年第3期361-364,共4页Chinese Journal of Applied Chemistry

基　　金：广东省科技攻关资助项目(2006B11801004)

摘　　要：通过改进反应溶剂,用Wittig反应合成了对特丁氧酰氧基苯乙烯,以中性Al2O3为固定相,正己烷为流动相,采用普通液相色谱分离提纯了混合产物,改进简化了分离方法。结果表明,所得目标产物对特丁氧酰氧基苯乙烯纯度达99%以上,产率为60%-70%,中间产物对特丁氧酰氧基苯甲醛可以定量合成,反应的副产物主要是三苯基氧化膦。对目标产物、中间产物和一些反应副产物进行了红外和核磁共振分析。p-tert-Butoxycarbonyloxystyrene was synthesized by Wittig reaction with changing solvent medium. The hybrid products were separated and purified by conventional liquid chromatography with neutral Al2O3 anhydrous column and n-hexane for elution, which simplifies the separation method. It was shown that the purity of the aim product was higher than 99% and its yield was 60% - 70%. The intermediate product p-tertbutoxycarbonyloxybenzaldehyde could be synthesized conveniently and quantitatively. The main byproduct was triphenylphosphine oxide. The aim product, intermediate product and some byproducts were identified with FTIR and NMR.

关 键 词：光致抗蚀剂 聚对羟基苯乙烯 对特丁氧酰氧基苯乙烯 

分 类 号：O621.3[理学—有机化学]