冠心Ⅱ号方水煎液纯化工艺方法比较  

Comparative Studies on the Purifying Conditions of the Elixation of the Guanxi Ⅱ decoction

作　　者：王锦玉[1] 冯伟红[1] 仝燕[1] 闫家福[1] 王智民[1] 朱晓新[1] 李连达[2] 

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]中国中医科学院西苑医院,北京100091

出　　处：《中国实验方剂学杂志》2007年第7期14-16,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家973项目-冠心二号配伍规律研究(2005CB523400)

摘　　要：目的:探讨冠心Ⅱ号方水煎液纯化工艺方法。方法:以除杂率、丹酚酸B等4种指标成分的含量为指标,对水煎液分别采用离心、醇沉、超滤膜过滤、澄清剂沉淀、大孔吸附树脂分离5种纯化工艺进行了比较研究。结果与结论:大孔吸附树脂分离法除杂率明显优于其它4种纯化方法,并可保留绝大部分有效成分。Objective：To compaire the purifying conditions for the elixation of the Guanxi Ⅱ decoction（GX- Ⅱ ）. Methods： Using the removal rate and the content of Salvianolic acid B and 3 other active ingredients as indexes. The purification of the elixation of the Guanxi Ⅱ decoction with 5 different conditions were compired, such as overspeed centrifugal, alcohol sedimentation, ultrafiltration membrane filtering, clarifier flocculation, and macroporous resin purifying etc. Result and Conclusion： The method of macroporous resin purification is superior to the other purification methods because it can reserve most parts of the active ingredients.

关 键 词：冠心Ⅱ号 纯化工艺 大孔吸附树脂 丹酚酸B 芍药苷 阿魏酸 羟基红花黄素A 

分 类 号：R286.3[医药卫生—中药学]