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作 者:曹秀峰[1] 肖建[1] 王山 吴必超 黄志华 黄水清[1] 王和明[1] 李义生[1] 朱斌[1]
机构地区:[1]南京医科大学附属南京第一医院肿瘤中心,南京210006 [2]江苏省盐城市肿瘤医院胸外科,224002
出 处:《临床肿瘤学杂志》2007年第6期441-444,共4页Chinese Clinical Oncology
摘 要:目的:总结1991年5月~2000年12月间71例食管癌患者行内翻拔脱术及其综合治疗的结果。方法:71例食管癌患者,中位年龄62岁。其中Ⅰ期40例,Ⅱa期26例,Ⅱb期4例,Ⅳ期1例,均采用食管内翻拔脱术治疗,接受术前辅助放疗4000cGy者9例,术后辅助放疗6000cGy者17例,术前新辅助化疗者5例。结果:术后1、3、5年的生存率为:Ⅰ期100.00%、91.43%、86.21%;Ⅱa期92.00%、83.33%、57.14%;Ⅱb期75.00%、50.00%、50.00%;Ⅳ期100.00%、0、0;全组71例患者1、3、5年总生存率分别为95.71%、86.89%、71.70%。并发症发生率为12.68%。结论:食管内翻拔脱术结合放、化疗将使不能耐受经胸或不需经胸手术的Ⅱa期及更早期的食管癌患者获益。Objective:The aim of this study was to analyze the results and introduce the experiences of transhiatal esophagectomy in combined With different synthetic therapy, Methods:Seventy-one patients with esophageal cancacinoma, median age was 62, 40 of stage Ⅰ ,26 of Ⅱ a,4 of stage Ⅱ b,1 of stage Ⅳ, were treated with transhiatal esophagectomy. 9 and 17 patients were treated with preoperative radiotherapy (4 000cGy) and postoperative adjuvant radiotherapy (6 000cGy ) respectively; 5 patients were treated with preoperative chemotherapy. Results:The postoperative 1,3 and 5 year survival rates were 100% ,91.43% ,86. 21% for stage Ⅰ ; 92% ,83.33% ,57. 14% for stage Iia;75% ,50% ,50% for stage Ⅱ b; 100% ,0,0 for stag Ⅳand 95.71% ,86. 89% ,71.70% as a whole. The incidence rate of complications was 12.68 %. Conclusion:Transhiatal esophagectomy combined with chemotherapy or radiotherapy may be beneficial to patients with esophageal carcinoma at stage Ⅱ a or earlier who can't tolerate or need not be treated by transthoracic esophagectomy.
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