2-氨基乙脒化二溴化氢盐的制备  

Synthesis of 2-amino-acetamidine dihydrobromide

作　　者：卢晗[1] 洪镛裕[1] 邓优华[1] 

机构地区：[1]华东师范大学化学系,上海200062

出　　处：《化学试剂》2007年第7期439-440,共2页Chemical Reagents

摘　　要：采用叔丁氧羰基(BOC)对2-氨基乙腈的氨基进行保护,在氨气的甲醇溶剂中催化形成脒,最后用无水溴化氢脱保护得到最终产物2-氨基乙脒化二溴化氢盐,经核磁鉴定为目标产物。Treatment of 2-aminoacetonitinle with di-tert- butyldicarbonate gave N-BOC-2-aminoacetonitrile, which was then catalyzed in the presence of ammonia and methanol to form amidine. The resultant 2-amino-acetamidine dihydrobremide was obtained after removal of the block groups with anhydrous hydro- bromide. Its structure was verified by 1HNMR.

关 键 词：2-氨基乙脒 催化 2-氨基乙脒化二溴化氢盐 

分 类 号：TQ612.1[化学工程—精细化工]