复方远桂知合剂对急性肝损伤大鼠血清SOD活性及MDA含量的影响  

Effects of the compounds Yuanguizhi on SOD and MDA in serum of the acute liver injury

作　　者：黄明姬[1] 崔敬爱[1] 

机构地区：[1]延边大学护理学院机能学教研室,吉林延吉133000

出　　处：《延边大学医学学报》2007年第2期103-104,共2页Journal of Medical Science Yanbian University

摘　　要：[目的]观察复方远桂知合剂对四氯化碳所致急性肝损伤大鼠血清SOD活性及MDA含量的影响.[方法]用四氯化碳制作大鼠急性肝损伤模型,采用比色分析法测定各组大鼠血清SOD活性及MDA含量.[结果]与模型组比较,复方远桂知合剂大、小剂量组急性肝损伤大鼠血清SOD活性显著提高,MDA含量明显降低.[结论]复方远桂知合剂具有清除自由基及抗脂质过氧化作用.OBJECTIVE To observe the effects of the compounds Yuanguizhi on superoxide dismutase （SOD） and malondialdehyde （MDA） in serum of the acute liver injury induced by carbon tetrachloride （CCl4） METHODS The acute liver injury model of rats was induced by CCl4. The activity of SOD and content of MDA in serum were measured by colorimetric method after treatment. RESULTS The activities of SOD in the compounds Yuanguizhi group were significantly higher and the content of MDA in the compounds Yuanguizhi group were obviously lower than model group in serum of the acute liver injury induced by CCl4. CONCLUSION The compounds Yuanguizhi could clear the flee radicals and has the effect of anti-lipid peroxidation

关 键 词：肝疾病 超氧化物歧化酶 丙二醛 植物 药用 大鼠 

分 类 号：R285.5[医药卫生—中药学]