利多卡因在白内障超声乳化吸出术中的应用  

Application of lidocaine in cataract phacoemulsification

作　　者：陈耀琴[1] 李卫红[1] 关山越[1] 

机构地区：[1]广东省肇庆市第二人民医院眼科,526060

出　　处：《眼科新进展》2007年第7期533-534,537,共3页Recent Advances in Ophthalmology

摘　　要：目的研究前房内注射利多卡因在白内障超声乳化吸出术中的散瞳和麻醉效果。方法将100例100眼老年性白内障患者随机分为利多卡因组和常规组进行超声乳化吸出术。记录2组患者术中瞳孔直径、麻醉效果及术后1d视力、瞳孔直径,术后1周角膜内皮细胞密度,并观察手术并发症的发生情况。结果利多卡因组和常规组术中瞳孔直径分别为(7.25±0.45)mm及(7.44±0.58)mm,术后1d瞳孔直径分别为(2.58±0.60)mm及(2.55±0.56)mm,2组比较差异无统计学意义(P>0.05)。2组患者术后1d视力均>0.5(利多卡因组:0.5～0.7者12眼,0.7～1.0者31眼,>1.0者7眼;常规组:0.5～0.7者13眼,0.7～1.0者29眼,>1.0者8眼),术后1周角膜内皮细胞丢失率分别为(5.92±1.48)%和(5.47±1.25)%,2组相比差异无统计学意义(P>0.05)。而利多卡因组麻醉效果明显优于常规组,差异有统计学意义(P<0.05)。结论白内障超声乳化吸出术中前房内注射不含防腐剂的体积分数1%利多卡因0.3～0.5mL,有扩瞳作用,不必术前常规散瞳,且麻醉效果好,安全可靠。Objective To investigate the effect of mydriasis and anesthesia of lidocaine after intracameral injection during cataract phacoemulsification. Methods One handred cases （100 eyes）with senile cataract were rardomly divided into two groups（ lidocaine group and routine group）. Pupil diameter, anesthesia effect, visual acuity, corneal endothelial cell density and other complications were recorded. Results Pupil diameters during operation in two groups were （7.25±0.45 ） mm and（7.44±0.58） mm, and which in post-operation was （ 2.58 ± 0. 60 ） mm and（2.55 ±0.56） mm respectively.The visual acuity at 1 day postoperatively in lidocaine group：12 cases were 0.5 ± 0.7,31 eases were 0. 7 ± 1.0,7 cases were 〉 1.0; Routine group： 13 cases were 0.5 ±0. 7,29 cases were 0. 7 - 1.0,8 cases were 〉 1.0. The corneal endothelial cell loss rate was （ 5.92 ± 1.48 ） % and （ 5.47 ± 1.25 ） % respectively. In comparison of the pupil diameter, visual acuity, and corneal endothelial cell loss, there was no statistically significant difference between two groups（P 〉 0.05 ）. But the difference was statistically significant on anesthesia effect （ P 〈 0. 05 ）, ndocaine group was better. Cenclusien During phacoemulsification, intracameral injection of lidocaine provides rapid, effective mydriasis and anesthesia. It is safe to use in clinic.

关 键 词：白内障 超声乳化吸出术 利多卡因 麻醉 

分 类 号：R776.1[医药卫生—眼科]