云南云县彝族、汉族地区幽门螺杆菌感染的流行病学调查  

Seroprevalence of Helicobacter pylori Infection among Yi and Han Nationalities in Yunxian County,Yunnan Province

作　　者：周曾芬[1] 张永生[1] 王玉明[1] 罗家洪[2] 查学安 崔蓉[1] 周崇斌[1] 

机构地区：[1]昆明医学院第一附属医院,650032 [2]昆明医学院预防医学系 [3]云南云县人民医院

出　　处：《中华流行病学杂志》1997年第1期18-21,共4页Chinese Journal of Epidemiology

摘　　要：在云南云县彝族、汉族地区用整群抽样方法对1184名自然人群进行前瞻性幽门螺杆菌（Hp）感染的血清学检测，并对其中325名同时检测抗-HAVIgG。结果发现：Hp总感染率为51．10％；彝、汉族感染率无差异。Hp感染随年龄增长而增加；饮用河水和生水明显高于饮用井水、自来水和开水；饲养家畜（禽）者明显高于未饲养者；吸毒者明显高于非吸毒者。Hp感染与HAV感染呈平行关系。多因素logistic最后筛选出饮用水源、饮水习惯、养鸡、养猪、养狗、吸毒和大蒜为Hp感染的7个重要流行因素。提示饮水是Hp感染的重要传播媒介；似支持Hp感染的动物来源理论和粪-口传播的观点；经常食用大蒜可起到长期人群防治Hp感染的作用。Under clusten sampling, an early serum eny of helicobacterpylori (Hp) infortion among1084 healthy people, was carried out. Out of them, 325 among the Yi and Han Nationalities at Yunxian County of Yunnan Province were given a simultaneous test of anti-HAV IgG. The results were asfollows: overall Hp infection rate was 51.1%; no difference of the infection was observed between the Yisand the Hans; the prevalence of Hp antibody went up with age; Higher rates were detected among those who drank river water or unboiled-water than among those who drank tap water, well water or boiled water, from poultry raisers than from non-poultry raisers and with drug abusers than with non-drugabusers. Hp infection showed a parallel relation to HAV infection. Finally, seven main epidemic factorswere sifted from multi-factor logistic analysis namely source of drinking water, drinking habit, chicken-raising, pig-keeping, dog-breeding, drug - abusing and consumption of garlic. All these findingr suggestedthat drinking water was an important vehicle of Hp infection. Our research data seems to have lendsupport to both fecal-oral transmission viewpoint and the hypothesis that Hp infection derives fromanimals. Frequent intake of garlic may serve as an agent in long - term prevention of Hp infection amongpeople in this area.

关 键 词：幽门螺杆菌 流行病学 ELISA 胃疾病 

分 类 号：R573.04[医药卫生—消化系统] R377.5[医药卫生—内科学]