青年人中原发性肝癌致病因素探讨  

A Study on the Multiple Factorial Causation of Hepatoma among Young Patients

作　　者：程明亮[1] 罗天永[1] 潘念齐[2] 冷祥康 黄堂珍[4] 

机构地区：[1]贵阳医学院附属医院,贵阳550004 [2]贵阳市第五人民医院 [3]安顺地区医院 [4]贵州省人民医院

出　　处：《中华流行病学杂志》1997年第1期37-39,共3页Chinese Journal of Epidemiology

基　　金：贵州省项目

摘　　要：采用病例-对照研究方法，对50例青年人原发性肝癌与病人住地附近“健康者”进行流行病学调查和致病多因素探讨。比较乙肝病毒（HBV）、丙肝病毒（HCV）感染、饮酒等多因素作用的大小。单因素分析表明，HBV感染、肝癌家族史与青年人肝癌关系密切，OR值分别为25、3倍。提示HBV感染在青年人肝癌中的作用远远高于其他危险因素。Pathogenetic significance of major risk factors to primary hepatoma among young people was invesigated through a case - control study. The analysis of single - factor showed that there was closerelationship between HBV infection, family history of hepatoma and the primary hepatocellular carcinomaatnong yOung mp1e, with an OR 25. 3. Multiple - factorial analysis indicated that the effect of HBVinfeCtbo far exceded other risk factors in the pathogeneSs of primary hepatoma, suggesting that HBVinfection might be a tnaor cause of primary hepatoma among young people.

关 键 词：肝肿瘤 病因 乙型肝炎病毒 丙型肝炎病毒 

分 类 号：R735.702[医药卫生—肿瘤]