血清肿瘤特异性生长因子(TSGF)检测在肺癌诊断及疗效观察中的应用价值  

Practical value of serum tumor specific growth factors in the diagnosis and treatment of lung cancer

作　　者：何力志[1] 吕岳峰[1] 王松华[1] 赵艳华[1] 

机构地区：[1]湖南省第二人民医院,湖南长沙410007

出　　处：《临床和实验医学杂志》2007年第7期11-11,13,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨血清肿瘤特异性生长因子(TSGF)在肺癌诊断及疗效判断中的应用价值。方法采用比色法测定86例肺癌病人、45例肺良性病变病人和42例健康人血清中TSGF水平,并进行比较。结果肺癌组血清中TSGF水平明显高于肺良性病变组及健康对照组(P<0.01);肺癌患者经治疗后TSGF水平明显下降(P<0.05),对肺癌患者诊断敏感性为81.4%,特异性为80.0%。结论TSGF检测具有敏感性高、特异性好,对于肺癌的早期诊断和观察疗效具有一定的临床价值。Objective To investigate the practical value of tumor specific growth factors （TSGF） in the diagnosis and treatment of lung cancer. Methods Serum TSGF was measured by chromatometry in 86 patients with lung cancer, 48 patients with benign pulmonary diseases and 42 healthy people. Results Serum TSGF levels were significantly elevated in patients with lung cancer as compared with patients with benign pulmonary diseases and healthy people （ P 〈 0. 05 ）. After treatment, serum TSGF levels were significantly decreased in patients with lung cancer, The sensitivity and specificity of TSGF for the diagnosis of lung cancer was 81.4 % and 80.0% , respectively. Conclusion Serum TSGF has a high sensitivity and specificity for the diagnosis of lung cancer. It is of value to the early diagnosis and effectiveness evaluation of lung cancer.

关 键 词：肺癌 TSGF 诊断 

分 类 号：R734.2[医药卫生—肿瘤]