高-低氧放疗临床应用的可行性探讨(附10例报告)  

CLINICAL APPLICATION OF RADIOTHERAPY WITH CARBOGEN PLUS OXYGEN IN DIFFERENT CONCENTRATIONS IN PATIENTS WITH MALIGNANT TUMOR: A REPORT OF 10 CASES

作　　者：刘山[1] 安永恒[1] 程熙国[1] 崔复宪[1] 焦升超[1] 

机构地区：[1]青岛大学医学院附属医院肿瘤科,山东青岛266003

出　　处：《齐鲁医学杂志》2007年第4期361-363,共3页Medical Journal of Qilu

摘　　要：目的探讨高-低氧放疗在临床应用中的可行性并初步评价其疗效及副作用。方法健康成年志愿者18例,检测其吸入不同浓度氧后生命体征(心率、呼吸、血压、血氧饱和度及心电图)的变化及耐受性。观察10例晚期、有腹部或盆腔复发或转移包块的恶性肿瘤病人在行高-低氧放疗时的耐受性,初步评价高-低氧放疗的有效率及副作用。结果健康成年志愿者吸入不同浓度氧后的主要生命体征无显著变化,10例病人在接受高-低氧放疗时未出现不能耐受的不良反应。结论对于具备适应证的病人,应用高-低氧放疗是安全的,具有一定的可行性。Objective To observe the clinical feasibility of carbogen plus low concentration oxygen radiotherapy （CPLCOR）. Methods Vital signs, ECG and tolerance of oxygen were checked among the healthy volunteers （n= 18） and advanced cancer patients with metastasis （n=10） after inhaling different concentrations of oxygen. Side-effects and effective power of CPLCOR were evaluated. Results No obvious changes in vital signs in the volunteers after inhaling different concentrations of oxygen were observed. The patients did not show intolerant side effects after receiving CPLCOR. Conclusion For cancer patients who are indicated CPLCOR is safe and feasible clinically.

关 键 词：高-低氧放疗 血氧饱和度 放射疗法 生命体征 

分 类 号：R73-36[医药卫生—肿瘤] R730.55[医药卫生—临床医学]