子宫乳头状浆液性腺癌25例临床病理分析  

Pathologic analysis on 25 cases of uterine papillary serous carcinoma

作　　者：胡春霞[1] 金松[1] 何超蔓[1] 吴玲[1] 纪武[2] 曹俊伟[1] 

机构地区：[1]海南医学院附属医院,海南海口570102 [2]海南省人民医院,海南海口570311

出　　处：《海南医学院学报》2007年第2期149-151,163,共4页Journal of Hainan Medical University

基　　金：海南省教育厅高校科研资助项目(Hjkj200747)

摘　　要：目的:探讨子宫乳头状浆液性腺癌(UPSC)的临床及病理特点。方法:回顾性分析25例UPSC患者的临床资料,对其临床及病理特点做统计学分析。结果:25例UPSC中,52%的病例肌层浸润深度超过1/2肌层(13/25),60%的病例有宫颈、阴道、卵巢或输卵管或宫旁、腹腔、大网膜等部位的子宫外转移(15/25),淋巴转移率为44%(11/25)。结论:UPSC病期晚,易浸润深肌层和向子宫外扩散,且病理分级、肌层浸润深度与淋巴转移、子宫外转移、腹水或腹腔冲洗液细胞学阳性之间无明显相关性;病理分级与子宫肌层浸润深度的发生率亦无显著性差异。术前应提高诊断率,提高手术分期的正确率,术后给予合理的个体化综合治疗,以期改善预后。Objective： To investigate the clinical and pathologic features of uterine papillary serous carcinoma （UPSC）. Methods： The clinical pathological data of 25 cases of UPSC were retrospectively analyzed. Results. 52%（13/25） cases had depth of myometrial invasion over 1/2.60% （15/25） cases had metastasis on cervix, vagina, ovaries, oviduct, parametrium, abdominal cavity and colic omentum. 44% （11/ 25） cases had lymph nodes metastasis. Conclusion： The advanced UPSC easily has depth of myometrial invasion and extended outside the uterus. The pathologic grade and the depth of myometrial invasion are not associated with the metastasis of lymph nodes and extrauterus, ascitic fluid and positive peritoneal washings cytology. Identification of the known risk factors by thorough preoperative evaluation and reasonable individual combined therapy postoperatively are very important to improve prognosis.

关 键 词：子宫肿瘤 腺癌 乳头状 病理学 临床 

分 类 号：R737.33[医药卫生—肿瘤]