康复新液联合潘托拉唑治疗消化性溃疡疗效分析  

Effeacy of Kangfuxin Liquid in combination with pantoprazole on peptic ulcer

作　　者：叶惠江[1] 王海勇[1] 求一秋[1] 

机构地区：[1]宁波市第一医院消化内科,浙江宁波315010

出　　处：《胃肠病学和肝病学杂志》2007年第3期274-276,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的研究康复新液与潘托拉唑联合治疗消化性溃疡(PU)的疗效。方法将经胃镜检查确诊的128例PU患者随机分为两组,治疗组65例,口服康复新液10ml每日3次,潘托拉唑40mg每日1次口服;对照组63例,口服潘托拉唑40mg每日1次。治疗期间每周1次随防,记录症状转归情况。疗程结束后,胃镜复查评估溃疡愈合情况。结果各项临床症状的改善和疼痛消失情况两组相比差异无显著性(P>0.05)。PU的愈合率和总有效率治疗组为95.4%和98.5%。对照组为82.5%和87.3%,两组相比差异有显著性(P<0.05)。两组在用药期间,不良反应少,均有良好的耐受性。结论康复新液联合潘托拉唑治疗PU可提高溃疡的愈合率和总有效率,缩短溃疡的愈合时间。Objective To observe the therapeutic effect of Kangfuxin Liquid in combination with pantoprazole on peptic ulcer. Methods One hundred and twenty eight patients with peptic ulcer diagnosed with gastroendoscopy were randomly divided into the study group（n = 65 ） and the control group（ n = 63 ）. Patients in the study group were treated with Kangfuxin Liquid orally, 10ml rid and pantoprazole 40mg qd. Patients in the control group were treated with pantoprazole 40mg qd. The course of treatment was 4 weeks. In the course of treatment, patients were followed up once a week, and the symptoms of the patients were recorded. After therapy course, the healing rate of ulcerative lesions was examined and evaluated by gastroendoscopy. Results There were no significant difference about clinical symptom improvement and pain relief between two groups（P 〉0.05）. The healing rate of ulcer was 95.4% and the effective rate was 98.5% in the study group, while 82.5% and 87.3% in control group. Their differences were obvious（P 〈 0.05）. The frequency of adverse events were low in both groups, and patients had well tolerability. Conclusion The treatment of Kangfuxin Liquid in combination with pantoprazole on peptic ulcer can improve the healing rate of ulcerative focus and the effective rate, shorten the healing time of ulcer.

关 键 词：消化性溃疡 康复新液 潘托拉唑 

分 类 号：R573[医药卫生—消化系统]