CT引导下经皮乙酸注射联合肝动脉化疗栓塞治疗原发性肝癌  

CT-guided percutaneous acetic acid injection combined with transcatheter arterial chemoembolization in the treatment of primary hepatocellular carcinoma

作　　者：周胜利[1] 张旭[1] 王宗盛[1] 吴华连[1] 

机构地区：[1]连云港市第一人民医院放射科,江苏省222002

出　　处：《介入放射学杂志》2007年第6期414-416,共3页Journal of Interventional Radiology

摘　　要：目的研究经导管肝动脉化疗栓塞(TACE)联合经皮乙酸注射(PAI)治疗原发性肝癌的疗效。方法选择52例肝癌患者,分为TACE联合PAI治疗组(26例)和单纯TACE组(26例),比较两组治疗效果。结果联合组与单纯TACE组AFP下降率为78.3%和50.0%,肿瘤体积缩小有效率分别为65.4%(17/26)和38.5%(10/26),1、2年生存率分别为73.1%(19/26)、38.5%(10/20)和57.7%(15/26)、19.2%(5/26),差异有统计学意义(P<0.05)。结论TACE联合PAI治疗原发性肝癌效果明显优于单纯TACE组。Objective To study the curative effect of CT-guided percutaneous acetic acid injection （PAl）combined with transcatheter arterial chemoembolization （TACE）in the treatment of primary heaptocellular carconima. Methods 52 cases with primary heaptocellular carconima were divided into two groups. 26 cases were treated with TACE and PAl, combined group comparing with other 26 cases treated with TACE group. Results Decrease of AFP, shrinkage of tumor mass and survival rate of 1-2 years of the combined group and TACE group were 78.3% vs 50.0%, 65.4%（17/26） vs 38.5%（lO/26）and 73.1%（19/26）, 52.6%（10/19） vs 57.7%（15/26）, 33.3%（5/15）, respectively; with statistical significance （P 〈 0.05）. Conclusion The curative effect of TACE with PAl is superior to TACE alone for patients with primary hepatocellular carcinoma. （J Intervent Radiol, 2007, 16： 414-416）

关 键 词：原发性肝癌 化学栓塞 乙酸 介入放射学 

分 类 号：R735.7[医药卫生—肿瘤]