脑梗死与血脂、血糖、血尿酸水平的关系探讨  

Relationship between cerebral infarction and levels of blood lipids,blood glucose and uric acid

作　　者：冯敏[1] 张友好[2] 

机构地区：[1]蚌埠医学院第二附属医院神经内科,安徽蚌埠233040 [2]蚌埠医学院第二附属医院检验科,安徽蚌埠233040

出　　处：《蚌埠医学院学报》2007年第4期429-430,共2页Journal of Bengbu Medical College

摘　　要：目的:探讨脑梗死患者血脂、血糖、血尿酸水平变化及其临床意义。方法:检测60例脑梗死患者的7项血脂指标以及血糖(GLU)、血尿酸(UA),并与对照组30例的检测结果进行比较。结果:脑梗死患者的胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B(ApoB)、脂蛋白(a)[Lp(a)]、GLU含量均高于对照组(P<0.05～P<0.001),载脂蛋白A1(ApoA1)含量显著低于对照组(P<0.001),UA和高密度脂蛋白(HDL)含量变化差异均无统计学意义(P>0.05)。结论:TC、TG、LDL、ApoB、Lp(a)、GLU的水平升高,ApoA1下降与脑梗死均有一定关系,应重视对高血脂、高血糖的积极防治。Objective：To explore the relationship between cerebral infarction （CI） and the levels of blood lipids, blood glucose and serum uiic acid. Methods： Seven indices of serum lipids and blood glucose （ GLU）, serum uric acid （UA） in 60 patients with CI （patient group） and 30 cases without CI （control group ） were measured and compared. Results：The serum levels of total cholesterol （ TC ） , triglyceride （TG） , low-density lipoprotein （ LDL ） , apolipoprotein B （ ApoB ） , lipoprotein （ a ） [ Lp （ a ） ] , GLU were obviously higher in the cerebral infarction group than those in the control group （ P 〈 0.05 - P 〈 0. 001 ）, but apolipoprotein A1 （ Apo A1 ） was significantly lower（ P 〈 0.001 ）. There was no significant difference in high-density lipoprotein （HDL） and UA levels between cerebral infarction group and control group （ P 〉 0.05 ）. Conclusions： The results suggest that the higher levels of TC, TG, LDL, ApoB, Lp （ a）, GLU and lower levels of ApoA1 are related to CI to a certain extent, which indicates that it is necessary to actively control and prevent the hyperlipidemia and the high blood glucose.

关 键 词：脑梗死 血脂过多 血糖过多 尿酸 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R589.2[医药卫生—临床医学]