老年2型糖尿病并发脑梗死患者经颅多普勒超声分析  

DETECTION OF CEREBRAL ARTERY IN AGED TYPE Ⅱ DIABETES PATIENTS WITH OR WITHOUT CEREBRAL INFARCTION BY TRANSCRANIAL DOPPLER ULTRASONOGRAPHY

作　　者：谢静芳[1] 黄雪芬[1] 郭智君[1] 胡方方[1] 

机构地区：[1]广东省人民医院,广东广州510080

出　　处：《现代医院》2007年第8期64-66,共3页Modern Hospitals

基　　金：2006年度省中医药局课题;项目编号:1060030

摘　　要：目的采用经颅多普勒(TCD)超声检测,观察并分析伴或不伴脑梗死老年2型糖尿病患者大脑动脉血流动力学变化及损伤血管分布情况,为临床防治提供依据。方法89例老年2型糖尿病患者根据有无并发脑梗死情况分为糖尿病无脑梗死组(47例)和糖尿病伴脑梗死组(42例),并以40例老年健康志愿者作为对照组。所有观察对象分别行大脑动脉TCD检测并行数据分析。结果①伴或不伴脑梗死的老年2型糖尿病患者大脑中动脉(MCA)、大脑前动脉(ACA)、大脑后动脉(PCA)、颈内动脉起始部(ICA)、基底动脉(BA)及椎动脉(VA)的收缩期峰血流速度(Vp)均较对照组明显增高(p<0.05)。糖尿病伴脑梗死组患者MCA、ACA、BA、ICA的Vp值较糖尿病无脑梗死组明显增高(p<0.05)。②老年2型糖尿病患者脑血管异常以血流速度增高为主的血管主要是MCA、ACA、BA和ICA。以血流速度减慢为主的血管主要是PCA、BA和VA。以血管狭窄为主的血管主要是MCA、BA和ICA。③无论伴或不伴脑梗死的糖尿病患者脑动脉血流异常累及血管数均明显多于正常对照组(p<0.05)。同时,伴有脑梗死的糖尿病患者其脑动脉血流异常累及血管数明显高于不伴脑梗死的患者(p<0.05)。结论老年2型糖尿病患者脑血管病变发生率高,如已伴发脑梗死其大脑动脉的病变程度更严重,需引起临床医生的高度重视。Objective To detect the cerebral artery in aged type Ⅱ diabetes patients with or without cerebral infarction by transcranial Doppler tdtrasonography. Method 89 cases of aged type Ⅱ diabetic patients were divided into two groups as diabetes with cerebral infarction group （ group 1 ） and diabetes without cerebral infarction group （group 2）. 40 cases health old people were selected as normal control. TCD examination were performed in all pa- tients and the data be analyzed. Results （1） The systolic peak flow velocity （Vp） of MCA, ACA, PCA, ICA, BA and VA were significant increased in both group 1 and group 2 patients when compared with normal control group （p 〈 0.05 ）. The Vp of MCA,ACA,BA,ICA in group 2 patient was significant higher than that in group 1 patients （p 〈 0.05）. （2） The cerebral homodynamic changes were common in aged type Ⅱ diabetes patients, fast Vp was seen in MCA,ACA,BA and ICA, low Vp was seen in PCA,BA and VA, and angiostenosis was seen in MCA,BA and ICA significantly. （3） The cerebral hemodynamic changed involved cerebral arteries in both with or without cerebral infarction groups were significant more than that in normal control group （p 〈 0.05 ）. And the number of involved cerebral arteries in groups 1 war more than that in group 2 （p 〈 0.05 ）. Conclusion The cerebrovascular disease is common in aged type Ⅱ diabetic patients and more serious in patients with cerebral infarction.

关 键 词：老年2型糖尿病 脑梗死 经颅多普勒超声 

分 类 号：R743[医药卫生—神经病学与精神病学]