白血病病人血清脂质结合唾液酸的测定  

LIPID BOUND SIALIC ACID IN SERA OF LEUKEMIA PATIENTS

作　　者：李广伦[1] 孟凡军[1] 马瑞欣[1] 

机构地区：[1]青岛医学院诊断学教研室

出　　处：《青岛医学院学报》1997年第1期65-66,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：①目的探讨血清脂质结合唾液酸（ＬＳＡ）含量对白血病诊断的意义。②方法用唾液酸快速诊断法测定４０例白血病病人及６０例健康人血清ＬＳＡ含量，对所得结果进行了比较，并观察了外周血白血病细胞数与ＬＳＡ的相关关系。③结果白血病病人血清ＬＳＡ含量明显高于对照组，两者差异有极显著性（ｔ＝４．４４，Ｐ＜０．００１），白血病细胞数和骨髓增生程度与ＬＳＡ含量均无明显相关关系（ｒ＝０．１７，－０．１３，Ｐ均＞０．０５）。④结论血清脂质结合唾液酸测定是诊断白血病的一个重要的辅助指标。Objective To study the significance of serum value of lipid bound sialic acid (LSA) in leukmia diagnosis. Methods LSA in serum was detected in 40 leukmia patients and 60 healthy people. Meanwhile, the relatonship was observed between the number of leukemic cells in the peripheral blood and serum LSA level. Result Serum LSA in leukemia patients was significantly higher than in the control group( t=4.440 P <0.001).There was no significant correlation between the number of leukemic cells and LSA. Conclusion Serum LSA is a useful index in leukemia diagnosis.

关 键 词：唾液酸类 白血病 白细胞计数 骨髓检查 LSA 

分 类 号：R733.704[医药卫生—肿瘤]