不同海拔胃癌高发地区幽门弯曲菌感染的对比性分析(附576例胃粘膜活检)  

Comparative Stady on Infection with Pyloric Winding Bacteria at Different Incidence Regions of Stomach cancer

作　　者：姜英 张瑛 蔺小倩[1,2,3] 聂明 

机构地区：[1]江苏省中医院病理科 [2]青海医学院附属医院理科 [3]山东省烟台市肿瘤医院病理科

出　　处：《齐鲁肿瘤杂志》1997年第2期119-120,共2页

摘　　要：胃粘膜活检５７６例，其中２７６例来自南京地区（Ａ组），３００例来自西宁地区（Ｂ组）。用碱性复红法染色观察幽门弯曲菌（ＣＰ）。结果“ＣＰ”检出率两组有极明显差异：Ａ组６９．６％，Ｂ组２１．０％，这揭示“ＣＰ”可能与两地区海拨，气侯地理、生活环境、饮食结构习惯等不同有关。两组中活动性胃炎“ＣＰ”检出率均显著高于各组总检出率，提示“ＣＰ”可能是活动性慢性胃炎发生的常见原因。两组同为胃癌高发地区，也说明幽门弯曲菌与胃癌的发生是否有关是值得进一步探讨的问题。Gastric mucosal biopsy were performed on Gastric mucosal biopsy 576 cases,of which 276 cases were collected from Nanjing rigion (Group A),300 from xining region(Group B).We observed CP through alkalinestain.As a result,the rate of tests of the CP in two groups were quite different.Group A was 69%,Group B 21 0%.This indicated that CP infection might ralate to the difference of elevation,climate,geographical and living environment, diet structure and diet habit,etc.CP positive rates of active chronic gastritis in two groups were obviously higher than those of the total tests of each group.This indicated that CP may be the common cause of active chronic gastritis.These two regions were exactly high incidence regions of stomach cancer.But CP positive rates were remarkably different.Whether CP related to the occurence of the cancer of stomach would be worth being further studied.

关 键 词：幽门弯曲菌 胃肿瘤 胃粘膜 活检 

分 类 号：R735.2[医药卫生—肿瘤]