头颈部病变CT灌注成像的初步研究  

Initial research of CT perfusion imaging for head and neck lesions

作　　者：张新捧[1] 叶兆祥[1] 肖建宇[1] 

机构地区：[1]天津医科大学肿瘤医院放射科,天津300060

出　　处：《天津医科大学学报》2007年第2期221-223,共3页Journal of Tianjin Medical University

摘　　要：目的:探讨CT灌注成像技术对头颈部良恶性病变的鉴别诊断价值。方法:对头颈部恶性肿瘤组33例、良性病变组17例行CT灌注成像扫描,盲法分析两组病例的时间密度曲线(TDC)和灌注参数的特点及差异。结果:良恶性病变组间的TDC形态不同,恶性肿瘤组的血容量(BV)、血流量(BF)和表面通透性(PS)值高于良性病变组,平均通过时间(MTT)值短于良性病变组,其差异均存在统计学意义(P<0.05)。结论:头颈部良恶性病变的CT灌注特点不同,CT灌注成像技术对头颈部良恶性病变的鉴别诊断有重要的应用价值。Objective： To explore the value of CT perfusion benign and malignant lesions in head and neck. Methods： CTP （CTP） imaging in differential diagnosis of was performed in 50 objectives： 33 in malignant tumor group, 17 in benign lesion group, the time-density curve （TDC）and the data of perfusion parameters were recorded and analyzed statistically. Results： The TDC feature between the two groups had difference. The average of blood volume（BV）, blood flow （BF） and permeability surface （PS） of the malignant tumors were higher than those of benign lesions, the average of mean transit time （MTT） was lower than that of benign lesions ,and they had statistical differences （P〈0.05）. Conclusion： The features of the CTP are different in benign and malignant lesions in head and neck, CTP is helpful for the differential diagnosis of them.

关 键 词：头颈部 恶性肿瘤 灌注成像 体层摄影术 X线计算机 

分 类 号：R739.91[医药卫生—肿瘤] R730.44[医药卫生—临床医学]