PTE-CT对肝炎性肝硬化并肝细胞癌的诊断价值  

Diagnosing value of ^(18)F-deoxyglucose positron emission tomography/computed tomography for hepatocellular carcinoma combined with post-hepatitis cirrhosis

作　　者：李正平[1] 周杰[2] 张昌庆[1] 杨建国[1] 赵金艺[1] 

机构地区：[1]解放军477医院普外科,湖北襄樊441021 [2]南方医科大学附属南方医院肝胆外科,广东广州510515

出　　处：《肝胆胰外科杂志》2007年第4期212-214,共3页Journal of Hepatopancreatobiliary Surgery

摘　　要：目的评价18F氟脱氧葡萄糖(18F-FDG)PET-CT诊断肝炎性肝硬化并肝细胞癌的价值。方法分析肝硬化并肝细胞肝癌行18F-FDGPET-CT检查22例,共36个病灶。根据FDG的摄取将病灶分为2种类型,A型病变部位摄取高于周围正常组织;B型与周围组织相近,与手术后病理结果对比。结果中分化肝细胞癌15个、低分化肝细胞癌8个病灶表现为A型,高分化肝细胞癌7个和肝脏再生性结节6个病灶为B型。结论18F-FDGPET-CT对高分化肝细胞癌诊断效果差,对中低分化肝细胞癌诊断效果好。18F-FDGPET-CT对肝脏的多个占位性病灶中单个病灶的良恶性鉴别有重要价值。Objective To evaluate the clinical value of ^18F-FDG PET/CT for diagnosis of hepatocellular carcinoma （HCC） in patients with post0hepatitis cirrhosis. Methods From January 2002 to Mmay 2002, twenty-two patients with post-hepatitis cirrhosis and HCC were undergone PET/CT, in whom 36 lesions were detected. The lesions were divided into two types according to the uptake of FDG： type A： FDG uptake was higher than that of the surrounding normal tissues; and type B： FGD uptake similar to the surroundg non-tumor liver tissues. If a mass felt in type A, it was concluded as a HCC, or a benigh tumor, then, the result was compared with postoperative histopathologic examination. Results Fifteen masses of moderately differentiated HCC and eight masses of poorly differentiated HCC were exhibited in type A, but 7 well differentiated HCC and 6 regenerative nodules beonged to type B. Conclusion The diagnostic effect of ^18F-FDG PET/CT for detection of moderately differentiated HCC or poorly differentiated HCC is high, but the detection of well differentiated HCC is low. If there are multiple lesions in the liver of post-hepatitis cirrhosis, ^18F-FDG PET/CT appears to be a valuable method for the discrimination of liver neoplasm from regenerative nodule.

关 键 词：肝细胞癌 肝硬化 脱氧葡萄糖 体层摄影术 发射型计算机 体层摄影术 X线计算机 

分 类 号：R735.7[医药卫生—肿瘤]